Austin Health

Title
Interaction between ferric carboxymaltose and denosumab causing severe hypocalcaemia and hypophosphataemia in a patient without chronic kidney disease.
Publication Date
2023-07
Author(s)
Muhandiramge, Jaidyn
Lee, Vivian
Tran, Monica
Ho, Lannie
Subject
denosumab
ferric carboxymaltose
hypocalcaemia
hypophosphataemia
osteoporosis
Type of document
Journal Article
OrcId
0000-0002-6999-802X
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DOI
10.1111/imj.16156
Abstract
Coadministration of ferric carboxymaltose and denosumab may cause hypocalcaemia and hypophosphataemia; however, this interaction is not well-described in the literature and has typically been described in patients with chronic kidney disease (CKD). We present a case of this interaction in a patient without preexisting CKD. We suggest the use of alternative iron preparations and an interval of at least 4 weeks between administrations.
Link
Citation
Internal Medicine Journal 2023-07; 53(7)
Jornal Title
Internal Medicine Journal
ISSN
1445-5994

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