Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/32885
Title: Challenges of Glycemic Control in People With Diabetes and Advanced Kidney Disease and the Potential of Automated Insulin Delivery.
Austin Authors: Lu, Jean C;Lee, Petrova;Ierino, Francesco;MacIsaac, Richard J;Ekinci, Elif I ;O'Neal, David
Affiliation: Department of Medicine, St Vincent's Hospital Melbourne, The University of Melbourne, Fitzroy, VIC, Australia
Department of Nephrology, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia
St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia
Department of Endocrinology and Diabetes, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia
Australian Centre for Accelerating Diabetes Innovations, The University of Melbourne, Parkville, VIC, Australia
Endocrinology
Medicine (University of Melbourne)
Issue Date: 10-May-2023
Date: 2023
Publication information: Journal of Diabetes Science and Technology 2023
Abstract: Diabetes is the leading cause of chronic kidney disease (CKD) and end-stage kidney disease in the world. It is known that maintaining optimal glycemic control can slow the progression of CKD. However, the failing kidney impacts glucose and insulin metabolism and contributes to increased glucose variability. Conventional methods of insulin delivery are not well equipped to adapt to this increased glycemic lability. Automated insulin delivery (AID) has been established as an effective treatment in patients with type 1 diabetes mellitus, and there is emerging evidence for their use in type 2 diabetes mellitus. However, few studies have examined their role in diabetes with concurrent advanced CKD. We discuss the potential benefits and challenges of AID use in patients with diabetes and advanced CKD, including those on dialysis.
URI: https://ahro.austin.org.au/austinjspui/handle/1/32885
DOI: 10.1177/19322968231174040
ORCID: 0000-0002-3151-232X
0000-0002-0870-4032
Journal: Journal of Diabetes Science and Technology
Start page: 19322968231174040
PubMed URL: 37162092
ISSN: 1932-2968
Type: Journal Article
Subjects: artificial pancreas
automated insulin delivery
chronic kidney disease
diabetes
dialysis
insulin pump
Appears in Collections:Journal articles

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