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Title: | Challenges of Glycemic Control in People With Diabetes and Advanced Kidney Disease and the Potential of Automated Insulin Delivery. | Austin Authors: | Lu, Jean C;Lee, Petrova;Ierino, Francesco;MacIsaac, Richard J;Ekinci, Elif I ;O'Neal, David | Affiliation: | Department of Medicine, St Vincent's Hospital Melbourne, The University of Melbourne, Fitzroy, VIC, Australia Department of Nephrology, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia Department of Endocrinology and Diabetes, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia Australian Centre for Accelerating Diabetes Innovations, The University of Melbourne, Parkville, VIC, Australia Endocrinology Medicine (University of Melbourne) |
Issue Date: | 10-May-2023 | Date: | 2023 | Publication information: | Journal of Diabetes Science and Technology 2023 | Abstract: | Diabetes is the leading cause of chronic kidney disease (CKD) and end-stage kidney disease in the world. It is known that maintaining optimal glycemic control can slow the progression of CKD. However, the failing kidney impacts glucose and insulin metabolism and contributes to increased glucose variability. Conventional methods of insulin delivery are not well equipped to adapt to this increased glycemic lability. Automated insulin delivery (AID) has been established as an effective treatment in patients with type 1 diabetes mellitus, and there is emerging evidence for their use in type 2 diabetes mellitus. However, few studies have examined their role in diabetes with concurrent advanced CKD. We discuss the potential benefits and challenges of AID use in patients with diabetes and advanced CKD, including those on dialysis. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/32885 | DOI: | 10.1177/19322968231174040 | ORCID: | 0000-0002-3151-232X 0000-0002-0870-4032 |
Journal: | Journal of Diabetes Science and Technology | Start page: | 19322968231174040 | PubMed URL: | 37162092 | ISSN: | 1932-2968 | Type: | Journal Article | Subjects: | artificial pancreas automated insulin delivery chronic kidney disease diabetes dialysis insulin pump |
Appears in Collections: | Journal articles |
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