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Title: Evolution of risk prediction models for post-operative mortality in patients with cirrhosis.
Austin Authors: Kalo, Eric;George, Jacob;Read, Scott;Majumdar, Avik;Ahlenstiel, Golo
Affiliation: Blacktown Clinical School, School of Medicine, Western Sydney University, Blacktown, NSW, 2148, Australia.
Storr Liver Centre, The Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, Westmead, NSW, 2145, Australia.
Victorian Liver Transplant Unit
The University of Melbourne, Melbourne, VIC, 3010, Australia.
Issue Date: 27-Mar-2023
Date: 2023
Publication information: Hepatology International 2023-06; 17(3)
Abstract: The perception of high surgical risk among patients with cirrhosis has resulted in a long-standing reluctance to operate. Risk stratification tools, first implemented over 60 years ago, have attempted to assess mortality risk among cirrhotic patients and ensure the best possible outcomes for this difficult to treat cohort. Existing postoperative risk prediction tools including the Child-Turcotte-Pugh (CTP) and Model for End-stage Liver Disease (MELD) provide some prediction of risk in counselling patients and their families but tend to overestimate surgical risk. More personalised prediction algorithms such as the Mayo Risk Score and VOCAL-Penn score that incorporate surgery-specific risks have demonstrated a significant improvement in prognostication and can ultimately aid multidisciplinary team determination of potential risks. The development of future risk scores will need to incorporate, first and foremost, predictive efficacy, but perhaps just as important is the feasibility and usability by front-line healthcare professionals to ensure timely and efficient prediction of risk for cirrhotic patients.
DOI: 10.1007/s12072-023-10494-0
ORCID: 0000-0003-0026-1457
Journal: Hepatology International
PubMed URL: 36971983
ISSN: 1936-0541
Type: Journal Article
Subjects: Cirrhosis
Surgical risk
Appears in Collections:Journal articles

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