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Title: Disseminated Invasive Mucormycosis Infection Following Autologous Stem Cell Transplantation for Diffuse Large B-Cell Lymphoma.
Austin Authors: Cliff, Edward R Scheffer;Reynolds, Gemma;Grigg, Andrew P 
Affiliation: Clinical Haematology
Infectious Diseases
Olivia Newton-John Cancer Research Institute
Issue Date: 8-Feb-2023 2023
Publication information: Clinical Hematology International 2023
Abstract: Invasive fungal infections (IFI) are challenging to predict, diagnose and treat, and are associated with a particularly high mortality among patients with hematological malignancies. They are relatively uncommon in patients with lymphoma, compared with those with acute leukemia or undergoing allogeneic transplantation. We present a patient, autografted for recurrent lymphoma, with fever and refractory diarrhea persisting post engraftment, eventually attributable to disseminated mucor infection. This case illustrates the challenge of timely diagnosis and initiation of treatment for IFI in lymphoma patients, who do not routinely receive antifungal prophylaxis, and the importance of aggressive investigation and symptom-directed tissue sampling for evidence of IFI in febrile immunocompromised hosts not responding to broad-spectrum antibiotics.
DOI: 10.1007/s44228-023-00031-z
Journal: Clinical Hematology International
Start page: 1
End page: 7
PubMed URL: 36750525
ISSN: 2590-0048
Type: Journal Article
Subjects: Autologous stem cell transplant
Invasive fungal infection
Appears in Collections:Journal articles

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