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https://ahro.austin.org.au/austinjspui/handle/1/32020| Title: | Risk of sudden unexpected death in epilepsy (SUDEP) with lamotrigine and other sodium channel modulating antiseizure medications. | Austin Authors: | Nightscales, Russell ;Barnard, Sarah;Laze, Juliana;Chen, Zhibin;Tao, Gerard;Auvrez, Clarissa;Sivathamboo, Shobi;Cook, Mark J;Kwan, Patrick;Friedman, Daniel;Berkovic, Samuel F ;D'Souza, Wendyl;Perucca, Piero ;Devinsky, Orrin;O'Brien, Terence J | Affiliation: | Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia. Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia. Department of Neurology, New York University Grossman School of Medicine, New York, NY, United States. Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia. Department of Medicine (The Royal Melbourne Hospital), The University of Melbourne, Victoria, Australia. Department of Neurology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia. Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia. Department of Medicine, St. Vincent's Hospital, The University of Melbourne, Fitzroy, Victoria, Australia. Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia. Department of Neurology, New York University Grossman School of Medicine, New York, NY, United States. General Medicine Department of Medicine, St. Vincent's Hospital, The University of Melbourne, Fitzroy, Victoria, Australia. Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia. Department of Neurology, New York University Grossman School of Medicine, New York, NY, United States. Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia. |
Issue Date: | 17-Jan-2023 | Date: | 2023 | Publication information: | Epilepsia open 2023; 8(2) | Abstract: | In vitro data prompted U.S Food and Drug Administration warnings that lamotrigine, a common sodium channel modulating anti-seizure medication (NaM-ASM), could increase risk of sudden death in patients with structural or ischaemic cardiac disease, however its implications for Sudden Unexpected Death in Epilepsy (SUDEP) are unclear. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/32020 | DOI: | 10.1002/epi4.12693 | ORCID: | 0000-0001-9108-207X 0000-0003-0517-2533 0000-0002-1888-6917 0000-0001-7310-276X 0000-0003-4580-841X 0000-0002-7855-7066 0000-0003-0044-4632 |
Journal: | Epilepsia Open | PubMed URL: | 36648376 | ISSN: | 2470-9239 | Type: | Journal Article |
| Appears in Collections: | Journal articles |
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