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Title: Case of leptospirosis causing pancytopenia.
Austin Authors: Haryono, Ian Satya;Tinson, Alistair John;Abasszade, Joshua Haron;O'Donnobhain, Ronan
Affiliation: General Internal Medicine Unit, Western Health, Saint Albans, Victoria, Australia
Geriatric Medicine
Department of General Medicine, Monash Health, Clayton, Victoria, Australia.
General Medicine
Issue Date: 5-Jan-2023 2023
Publication information: BMJ Case Reports 2023; 16(1)
Abstract: We present the case of a young female landscaper who presented to an Australian tertiary hospital with persistent fevers and new pancytopenia. Extensive initial workup for her presenting illness did not identify a cause; however, a detailed history of her occupation revealed she worked heavily with soil on farms that had domestic livestock in addition to rodents. Hence, further serological testing for leptospirosis was performed, revealing a diagnosis of infection with Leptospira interrogans serovar Hardjo. Treatment covering leptospirosis was commenced, and she improved clinically, and her cell counts returned to normal. Pancytopenia is a rare manifestation of leptospirosis and has only been reported in a handful of case studies. We highlight that leptospirosis should be considered as a differential diagnosis in those with fever, and new pancytopaenia, particularly in patients with relevant risk factors for exposure.
DOI: 10.1136/bcr-2022-251506
ORCID: 0000-0001-6372-3781
Journal: BMJ Case Reports
PubMed URL: 36604107
ISSN: 1757-790X
Type: Journal Article
Subjects: Infectious diseases
Medical education
Leptospirosis/drug therapy
Appears in Collections:Journal articles

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