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Title: | Fenfluramine treatment is associated with improvement in everyday executive function in preschool-aged children (<5 years) with Dravet syndrome: A critical period for early neurodevelopment. | Austin Authors: | Bishop, Kim I;Isquith, Peter K;Gioia, Gerard A;Knupp, Kelly G;Scheffer, Ingrid E ;Nabbout, Rima;Specchio, Nicola;Sullivan, Joseph;Auvin, Stéphane;Helen Cross, J;Guerrini, Renzo;Farfel, Gail;Galer, Bradley S;Gammaitoni, Arnold R | Affiliation: | Global Pharma Consultancy, LLC, Muncy, PA, USA; Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Global Pharma Consultancy, LLC, Muncy, PA, USA; Children's National Health System, Rockville, MD, USA. Children's Hospital Colorado, Aurora, CO, USA. University of Melbourne and Royal Children's Hospitals, Florey Institute and Murdoch Children's Research Institute, Melbourne, Victoria, Australia. Reference Centre for Rare Epilepsies, Hôpital Universitaire Necker-Enfants Malades, APHP, Member of EPICARE, Institut Imagine, Université Paris Cité, Paris, France. Rar Bambino Gesù Children's Hospital IRCCS, Rome, Italy. University of California San Francisco, Benioff Children's Hospital, San Francisco, CA, USA. Robert Debré Children's Hospital, APHP, Université de Paris, Paris, France; Institut Universitaire de France (IUF), Paris, France. UCL NIHR BRC Great Ormond Street Institute of Child Health, London, UK. Anna Meyer Children's Hospital, University of Florence, Florence, Italy. Formerly Zogenix, Inc., now a part of UCB, Emeryville, CA, USA. Epilepsy Research Centre |
Issue Date: | Jan-2023 | Date: | 2022 | Publication information: | Epilepsy & behavior : E&B 2023; 138:108994 | Abstract: | To evaluate whether fenfluramine (FFA) is associated with improvement in everyday executive function (EF)-self-regulation-in preschool-aged children with Dravet syndrome (DS). | URI: | https://ahro.austin.org.au/austinjspui/handle/1/31952 | DOI: | 10.1016/j.yebeh.2022.108994 | ORCID: | Journal: | Epilepsy & behavior : E&B | Start page: | 108994 | PubMed URL: | 36463826 | ISSN: | 1525-5069 | Type: | Journal Article | Subjects: | Behavior Rating Inventory of Executive Function® Dravet syndrome Executive function Fenfluramine Neurodevelopment Epilepsies, Myoclonic/drug therapy Executive Function/physiology Fenfluramine/therapeutic use Fenfluramine/pharmacology Parents/psychology |
Appears in Collections: | Journal articles |
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