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Title: Fenfluramine treatment is associated with improvement in everyday executive function in preschool-aged children (<5 years) with Dravet syndrome: A critical period for early neurodevelopment.
Austin Authors: Bishop, Kim I;Isquith, Peter K;Gioia, Gerard A;Knupp, Kelly G;Scheffer, Ingrid E ;Nabbout, Rima;Specchio, Nicola;Sullivan, Joseph;Auvin, Stéphane;Helen Cross, J;Guerrini, Renzo;Farfel, Gail;Galer, Bradley S;Gammaitoni, Arnold R
Affiliation: Global Pharma Consultancy, LLC, Muncy, PA, USA; Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Global Pharma Consultancy, LLC, Muncy, PA, USA; Children's National Health System, Rockville, MD, USA.
Children's Hospital Colorado, Aurora, CO, USA.
University of Melbourne and Royal Children's Hospitals, Florey Institute and Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
Reference Centre for Rare Epilepsies, Hôpital Universitaire Necker-Enfants Malades, APHP, Member of EPICARE, Institut Imagine, Université Paris Cité, Paris, France.
Rar Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
University of California San Francisco, Benioff Children's Hospital, San Francisco, CA, USA.
Robert Debré Children's Hospital, APHP, Université de Paris, Paris, France; Institut Universitaire de France (IUF), Paris, France.
UCL NIHR BRC Great Ormond Street Institute of Child Health, London, UK.
Anna Meyer Children's Hospital, University of Florence, Florence, Italy.
Formerly Zogenix, Inc., now a part of UCB, Emeryville, CA, USA.
Epilepsy Research Centre
Issue Date: Jan-2023
Date: 2022
Publication information: Epilepsy & behavior : E&B 2023; 138:108994
Abstract: To evaluate whether fenfluramine (FFA) is associated with improvement in everyday executive function (EF)-self-regulation-in preschool-aged children with Dravet syndrome (DS).
DOI: 10.1016/j.yebeh.2022.108994
Journal: Epilepsy & behavior : E&B
Start page: 108994
PubMed URL: 36463826
ISSN: 1525-5069
Type: Journal Article
Subjects: Behavior Rating Inventory of Executive Function®
Dravet syndrome
Executive function
Epilepsies, Myoclonic/drug therapy
Executive Function/physiology
Fenfluramine/therapeutic use
Appears in Collections:Journal articles

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