Hepatitis B Virus Flares After Nucleot(s)ide Analogue Cessation Are Associated With Activation of Toll-Like Receptor Signaling Pathways.

Hall, Samuel A L; Burns, Gareth S; Mooney, Benjamin J; Millen, Rosemary; Morris, Rachel; Vogrin, Sara; Sundararajan, Vijaya; Ratnam, Dilip; Levy, Miriam T; Lubel, John S; Nicoll, Amanda J; Strasser, Simone I; Sievert, William; Desmond, Paul V; Ngu, Meng C; Angus, Peter W; Sinclair, Marie; Meredith, Christopher; Matthews, Gail; Revill, Peter A; Jackson, Kathy; Littlejohn, Margaret; Bowden, Scott; Locarnini, Stephen A; Thompson, Alexander J; Visvanathan, Kumar

doi:10.1093/infdis/jiac375

Title

Hepatitis B Virus Flares After Nucleot(s)ide Analogue Cessation Are Associated With Activation of Toll-Like Receptor Signaling Pathways.

Publication Date

2022-12-28

Author(s)

Hall, Samuel A L

Burns, Gareth S

Mooney, Benjamin J

Millen, Rosemary

Morris, Rachel

Vogrin, Sara

Sundararajan, Vijaya

Ratnam, Dilip

Levy, Miriam T

Lubel, John S

Nicoll, Amanda J

Strasser, Simone I

Sievert, William

Desmond, Paul V

Ngu, Meng C

Angus, Peter W

Sinclair, Marie

Meredith, Christopher

Matthews, Gail

Revill, Peter A

Jackson, Kathy

Littlejohn, Margaret

Bowden, Scott

Locarnini, Stephen A

Thompson, Alexander J

Visvanathan, Kumar

Subject

cessation

entecavir

flare

hepatitis B virus

tenofovir

Type of document

Journal Article

OrcId

0000-0001-7158-585X

#PLACEHOLDER_PARENT_METADATA_VALUE#

DOI

10.1093/infdis/jiac375

Abstract

We evaluated the patterns of peripheral Toll-like receptor (TLR) signaling activity and the expression of TLRs and natural killer (NK) cell activation in a cohort of patients experiencing severe hepatitis flares after stopping nucleot(s)ide analogues (NAs) therapy.

Link

link

Citation

The Journal of Infectious Diseases 2022; 227(1)

Jornal Title

The Journal of Infectious Diseases

ISSN

1537-6613

Austin Health

Files: