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https://ahro.austin.org.au/austinjspui/handle/1/31848| Title: | Investigating Tissue-Specific Abnormalities in Alzheimer's Disease with Multi-Shell Diffusion MRI. | Austin Authors: | Giraldo, Diana L;Smith, Robert E;Struyfs, Hanne;Niemantsverdriet, Ellis;De Roeck, Ellen;Bjerke, Maria;Engelborghs, Sebastiaan;Romero, Eduardo;Sijbers, Jan;Jeurissen, Ben | Affiliation: | Computer Imaging and Medical Applications Laboratory - Cim@Lab, Universidad Nacional de Colombia, Bogotá, Colombia. The Florey Institute of Neuroscience and Mental Health Reference Center for Biological Markers of Dementia (BIODEM), Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium. imec-Vision Lab, Department of Physics, University of Antwerp, Antwerp, Belgium. |
Issue Date: | Dec-2022 | Publication information: | Journal of Alzheimer's Disease 2022 | Abstract: | Most studies using diffusion-weighted MRI (DW-MRI) in Alzheimer's disease (AD) have focused their analyses on white matter (WM) microstructural changes using the diffusion (kurtosis) tensor model. Although recent works have addressed some limitations of the tensor model, such as the representation of crossing fibers and partial volume effects with cerebrospinal fluid (CSF), the focus remains in modeling and analyzing the WM. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/31848 | DOI: | 10.3233/JAD-220551 | ORCID: | Journal: | Journal of Alzheimer's Disease | Start page: | 1771 | End page: | 1791 | PubMed URL: | 36336929 | ISSN: | 1875-8908 | Type: | Journal Article | Subjects: | Alzheimer’s disease cerebrospinal fluid cognitive dysfunction dementia diffusion MRI gray matter whitematter Alzheimer Disease/diagnostic imaging White Matter/diagnostic imaging White Matter/anatomy & histology Brain/diagnostic imaging Brain/anatomy & histology |
| Appears in Collections: | Journal articles |
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