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Title: Effects of changes in inspired oxygen fraction on urinary oxygen tension measurements.
Austin Authors: Osawa, Eduardo A;Cutuli, Salvatore L ;Yanase, Fumitaka ;Iguchi, Naoya;Bitker, Laurent;Maciel, Alexandre T;Lankadeva, Yugeesh R;May, Clive N;Evans, Roger G;Eastwood, Glenn M ;Bellomo, Rinaldo 
Affiliation: Imed Group Research Department, Sao Paulo, Brazil.
Dipartimento di Scienze dell'Emergenza, Anestesiologiche e della Rianimazione, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Intensive Care
Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, VIC, Australia
Service de Médecine Intensive - Réanimation, Hôpital de La Croix Rousse, Hospices Civils de Lyon, Lyon, France.
Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Australia
Cardiovascular Disease Program, Biomedicine Discovery Institute and Department of Physiology, Monash University, Melbourne, Australia
The Florey Institute of Neuroscience and Mental Health
Issue Date: 12-Dec-2022
Date: 2022
Publication information: Intensive Care Medicine Experimental 2022; 10(1)
Abstract: Continuous measurement of urinary PO2 (PuO2) is being applied to indirectly monitor renal medullary PO2. However, when applied to critically ill patients with shock, its measurement may be affected by changes in FiO2 and PaO2 and potential associated O2 diffusion between urine and ureteric or bladder tissue. We aimed to investigate PuO2 measurements in septic shock patients with a fiberoptic luminescence optode inserted into the urinary catheter lumen in relation to episodes of FiO2 change. We also evaluated medullary and urinary oxygen tension values in Merino ewes at two different FiO2 levels.
DOI: 10.1186/s40635-022-00479-y
ORCID: 0000-0002-1650-8939
Journal: Intensive Care Medicine Experimental
Start page: 52
PubMed URL: 36504004
Type: Journal Article
Subjects: Inspired oxygen fraction
Septic shock
Urinary oxygen tension
Urinary oxygenation
Appears in Collections:Journal articles

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