Austin Health

Title
Cerebrospinal fluid levels of fatty acid-binding protein 3 are associated with likelihood of amyloidopathy in cognitively healthy individuals.
Publication Date
2022-12
Author(s)
Dhiman, Kunal
Villemagne, Victor L
Fowler, Christopher
Bourgeat, Pierrick
Li, Qiao-Xin
Collins, Steven
Rowe, Christopher C
Masters, Colin L
Ames, David
Blennow, Kaj
Zetterberg, Henrik
Martins, Ralph N
Gupta, Veer
Subject
Alzheimer's disease
amyloid
early diagnosis
risk prediction
screening
Type of document
Journal Article
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DOI
10.1002/dad2.12377
Abstract
Fatty acid-binding protein 3 (FABP3) is a biomarker of neuronal membrane disruption, associated with lipid dyshomeostasis-a notable Alzheimer's disease (AD) pathophysiological change. We assessed the association of cerebrospinal fluid (CSF) FABP3 levels with brain amyloidosis and the likelihood/risk of developing amyloidopathy in cognitively healthy individuals.
Link
link
Citation
Alzheimer's and Dementia 2022
Jornal Title
Alzheimer's and Dementia

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