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https://ahro.austin.org.au/austinjspui/handle/1/31804| Title: | Baseline Characteristics and Representativeness of Participants in the BEST-Fluids Trial: A Randomized Trial of Balanced Crystalloid Solution Versus Saline in Deceased Donor Kidney Transplantation. | Austin Authors: | Collins, Michael G;Fahim, Magid A;Pascoe, Elaine M;Hawley, Carmel M;Johnson, David W;Varghese, Julie;Hickey, Laura E;Clayton, Philip A;Gill, John S;Dansie, Kathryn B;McConnochie, Rachael C;Vergara, Liza A;Kiriwandeniya, Charani;Reidlinger, Donna;Mount, Peter F ;Weinberg, Laurence ;McArthur, Colin J;Coates, P Toby;Endre, Zoltan H;Goodman, David;Howard, Kirsten;Howell, Martin;Jamboti, Jagadish S;Kanellis, John;Laurence, Jerome M;Lim, Wai H;McTaggart, Steven J;O'Connell, Philip J;Pilmore, Helen L;Wong, Germaine;Chadban, Steven J | Affiliation: | Central Northern Adelaide Renal and Transplantation Service, Royal Adelaide Hospital, Adelaide, Australia. Australasian Kidney Trials Network, The University of Queensland, Brisbane, Australia. Division of Nephrology, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada. Faculty of Medical and Health Sciences, The University of Adelaide, Adelaide, Australia. Department of Critical Care Medicine, Auckland City Hospital, Auckland, New Zealand. Anaesthesia Nephrology Anaesthesia Department of Nephrology, Prince of Wales Hospital, Randwick, Sydney, Australia. Department of Nephrology, St. Vincent's Hospital, Melbourne, Australia. School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia. Department of Nephrology and Renal Transplantation, Fiona Stanley Hospital, Murdoch, WA, Australia. Department of Nephrology, Monash Health, Clayton, Victoria, Australia. Institute of Academic Surgery, Royal Prince Alfred Hospital, University of Sydney, Sydney, NSW, Australia. School of Medicine, University of Western Australia, Perth, WA, Australia. Child and Adolescent Renal Service, Queensland Children's Hospital, Brisbane, QLD, Australia. Centre for Transplant and Renal Research, Westmead Institute for Medical Research, University of Sydney, NSW, Australia. Department of Renal Medicine, Auckland City Hospital, Auckland, New Zealand. General Medicine Department of Renal Medicine, Kidney Centre, Royal Prince Alfred Hospital, Sydney, Australia. |
Issue Date: | Dec-2022 | Date: | 2022 | Publication information: | Transplantation Direct 2022 | Abstract: | Delayed graft function (DGF) is a major complication of deceased donor kidney transplantation. Saline (0.9% sodium chloride) is a commonly used intravenous fluid in transplantation but may increase the risk of DGF because of its high chloride content. Better Evidence for Selecting Transplant Fluids (BEST-Fluids), a pragmatic, registry-based, double-blind, randomized trial, sought to determine whether using a balanced low-chloride crystalloid solution (Plasma-Lyte 148) instead of saline would reduce DGF. We sought to evaluate the generalizability of the trial cohort by reporting the baseline characteristics and representativeness of the trial participants in detail. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/31804 | DOI: | 10.1097/TXD.0000000000001399 | ORCID: | Journal: | Transplantation Direct | Start page: | e1399 | PubMed URL: | 36479278 | Type: | Journal Article |
| Appears in Collections: | Journal articles |
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