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https://ahro.austin.org.au/austinjspui/handle/1/31781| Title: | Radiomics-Derived Brain Age Predicts Functional Outcome After Acute Ischemic Stroke. | Austin Authors: | Bretzner, Martin;Bonkhoff, Anna K;Schirmer, Markus D;Hong, Sungmin;Dalca, Adrian;Donahue, Kathleen;Giese, Anne-Katrin;Etherton, Mark R;Rist, Pamela M;Nardin, Marco;Regenhardt, Robert W;Leclerc, Xavier;Lopes, Renaud;Gautherot, Morgan;Wang, Clinton;Benavente, Oscar R;Cole, John W;Donatti, Amanda;Griessenauer, Christoph;Heitsch, Laura;Holmegaard, Lukas;Jood, Katarina;Jimenez-Conde, Jordi;Kittner, Steven J;Lemmens, Robin;Levi, Christopher R;McArdle, Patrick F;McDonough, Caitrin W;Meschia, James F;Phuah, Chia-Ling;Rolfs, Arndt;Ropele, Stefan;Rosand, Jonathan;Roquer, Jaume;Rundek, Tatjana;Sacco, Ralph L;Schmidt, Reinhold;Sharma, Pankaj;Slowik, Agnieszka;Sousa, Alessandro;Stanne, Tara M;Strbian, Daniel;Tatlisumak, Turgut;Thijs, Vincent N ;Vagal, Achala;Wasselius, Johan;Woo, Daniel;Wu, Ona;Zand, Ramin;Worrall, Bradford B;Maguire, Jane;Lindgren, Arne G;Jern, Christina;Golland, Polina;Kuchcinski, Grégory;Rost, Natalia S | Affiliation: | Department of Neurology, John Hunter Hospital, Newcastle, NSW, Australia. J. Philip Kistler Stroke Research Center, Massachusetts General Hospital, Boston School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia Univ. Lille, Inserm, CHU Lille, U1172 - LilNCog - Lille Neuroscience & Cognition, F-59000 Lille, France. Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41 - UMS 2014 - PLBS, F-59000 Lille, France. Department of Medicine, Division of Neurology, University of British Columbia, Vancouver, British Columbia, Canada. Department of Neurology, University of Maryland School of Medicine and Veterans Affairs Maryland Health Care System, Baltimore, MD, USA. Department of Neurosurgery, Geisinger, Danville, PA, USA. Division of Emergency Medicine, Washington University School of Medicine, St Louis, MO, USA. Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden; Department of Neurology, Sahlgrenska University Hospital, Gothenburg, Sweden. Department of Neurology, Neurovascular Research Group (NEUVAS), IMIM-Hospital del Mar (Institut Hospital del Mar d'Investigacions Mèdiques), Universitat Autonoma de Barcelona, Barcelona, Spain. KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium; VIB, Vesalius Research Center, Laboratory of Neurobiology, University Hospitals Leuven, Department of Neurology, Leuven, Belgium. Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, University of Florida, Gainesville, FL, USA. Department of Neurology, Mayo Clinic, Jacksonville, FL, USA. Department of Neurology, Washington University School of Medicine & Barnes-Jewish Hospital, St Louis, MO, USA. Klinik und Poliklinik für Neurologie, Universitätsmedizin Rostock, Rostock, Germany. Department of Neurology, Clinical Division of Neurogeriatrics, Medical University Graz, Graz, Austria. Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA; Broad Institute, Cambridge, MA, USA. Department of Neurology and Evelyn F. McKnight Brain Institute, Miller School of Medicine, University of Miami, Miami, FL, USA. Department of Neurology, Clinical Division of Neurogeriatrics, Medical University Graz, Graz, Austria. Institute of Cardiovascular Research, Royal Holloway University of London (ICR2UL), Egham, UK St Peter's and Ashford Hospitals, UK. Department of Neurology, Jagiellonian University Medical College, Krakow, Poland. School of Medical Sciences, University of Campinas (UNICAMP) and the Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), Campinas, SP, Brazil. Division of Neurocritical Care & Emergency Neurology, Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland. The Florey Institute of Neuroscience and Mental Health Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA. Department of Clinical Sciences Lund, Radiology, Lund University, Lund, Sweden; Department of Radiology, Neuroradiology, Skåne University Hospital, Malmö, Sweden. Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA. A.A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, USA. Department of Neurology, Geisinger, Danville, PA, USA. Departments of Neurology and Public Health Sciences, University of Virginia, Charlottesville, VA, USA. University of Technology Sydney, Sydney, Australia. Section of Neurology, Skåne University Hospital, Lund, Sweden. Institute of Biomedicine, Department of Laboratory Medicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, Cambridge, USA. |
Issue Date: | 21-Feb-2023 | Date: | 2022-11 | Publication information: | Neurology 2023 | Abstract: | While chronological age is one of the most influential determinants of post-stroke outcomes, little is known of the impact of neuroimaging-derived biological "brain age". We hypothesized that radiomics analyses of T2-FLAIR images texture would provide brain age estimates and that advanced brain age of stroke patients will be associated with cardiovascular risk factors and worse functional outcomes. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/31781 | DOI: | 10.1212/WNL.0000000000201596 | ORCID: | 0000-0001-9561-0239 0000-0002-2425-2283 0000-0001-9263-8930 0000-0002-2623-6199 0000-0002-4948-5956 0000-0002-4475-8142 0000-0001-5992-2606 0000-0002-7115-9815 0000-0001-9095-2344 0000-0002-6614-8417 0000-0003-1896-381X 0000-0002-5509-9461 0000-0002-9477-0094 0000-0001-9386-4091 |
Journal: | Neurology | PubMed URL: | 36443016 | ISSN: | 1526-632X | Type: | Journal Article |
| Appears in Collections: | Journal articles |
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