Austin Health

Title
Plasma p-tau181/Aβ1-42 ratio predicts Aβ-PET status and correlates with CSF-p-tau181/Aβ1-42 and future cognitive decline.
Publication Date
2022
Author(s)
Fowler, Christopher J
Stoops, Erik
Rainey-Smith, Stephanie R
Vanmechelen, Eugeen
Vanbrabant, Jeroen
Dewit, Nele
Mauroo, Kimberley
Maruff, Paul
Rowe, Christopher C
Fripp, Jurgen
Li, Qiao-Xin
Bourgeat, Pierrick
Collins, Steven J
Martins, Ralph N
Masters, Colin L
Doecke, James D
Subject
Alzheimer's disease
amyloid beta amyloid imaging
blood biomarkers
blood diagnostic for Alzheimer's disease
cerebrospinal fluid
phosphorylated tau
plasma amyloid beta
plasma phosphorylated tau181
positron emission tomography
Type of document
Journal Article
OrcId
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#PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
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0000-0003-2863-0293
DOI
10.1002/dad2.12375
Abstract
In Alzheimer's disease (AD), plasma amyloid beta (Aβ)1-42 and phosphorylated tau (p-tau) predict high amyloid status from Aβ positron emission tomography (PET); however, the extent to which combination of these plasma assays can predict remains unknown.
Link
link
Citation
Alzheimer's and Dementia 2022
Jornal Title
Alzheimer's and Dementia

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