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Title: A primer on cohort studies in vascular surgery research.
Austin Authors: Kabeil, Mahmood;Gillette, Riley;Moore, Ethan;Cuff, Robert F;Chuen, Jason ;Wohlauer, Max V
Affiliation: Division of Vascular Surgery, University of Colorado, Anschutz Medical Campus, CO.
Department of Surgery, University of Colorado, Anschutz Medical Campus, CO.
Spectrum Health, Grand Rapids, MI.
Vascular Surgery
Division of Vascular Surgery, University of Colorado, Anschutz Medical Campus, CO.
Issue Date: Dec-2022
Date: 2022
Publication information: Seminars in Vascular Surgery 2022; 35(4)
Abstract: Vascular research questions can be answered using various study designs. Observational studies are used frequently to address a wide range of clinical questions when randomized clinical trials are not feasible or practical. One of the powerful vascular research tools is the cohort study. The cohort study is a reliable observational study design in which individuals who share a common characteristic (a cohort) are followed over time and their outcomes are assessed at various intervals. This review focuses on the essential characteristics, design, implementation, bias, validity, and clinical significance of cohort studies and provides illustrative examples. A cohort study can be either a prospective or a retrospective study, depending on whether the outcome occurred before or after the enrollment of the cohort. Each type has its advantages and disadvantages. Confounding, selection, and information biases can all occur in cohort studies. Applications of the cohort study design include studying the natural history of a disease, describing a condition's frequency, and investigating multiple outcomes simultaneously.
DOI: 10.1053/j.semvascsurg.2022.09.004
Journal: Seminars in Vascular Surgery
Start page: 404
End page: 412
PubMed URL: 36414356
ISSN: 1558-4518
Type: Journal Article
Subjects: Vascular Surgical Procedures/adverse effects
Appears in Collections:Journal articles

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