Austin Health

Title
A low serum alkaline phosphatase may signal hypophosphatasia in osteoporosis clinic patients.
Publication Date
2023
Author(s)
Ng, Elisabeth
Ashkar, Claudia
Seeman, Ego
Schneider, Hans G
Nguyen, Hanh
Ebeling, Peter R
Sztal-Mazer, Shoshana
Subject
Alkaline phosphatase
Bisphosphonate
Hypophosphatasemia
Hypophosphatasia
Osteoporosis
Type of document
Journal Article
OrcId
0000-0001-6649-032X
#PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
DOI
10.1007/s00198-022-06597-3
Abstract
Low serum alkaline phosphatase (ALP) was found in 9% of patients attending an osteoporosis clinic, 0.6% of hospital patients, and 2/22 with an atypical femoral fracture. Hypophosphatasia was diagnosed in 3% of osteoporosis clinic patients with low ALP. Low ALP is a screening tool for hypophosphatasia, a condition potentially aggravated by antiresorptive therapy.
Link
Citation
Osteoporosis International 2023; 34(2)
Jornal Title
Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
ISSN
1433-2965

Files:

NameSizeformatDescriptionLink