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Title: | A low serum alkaline phosphatase may signal hypophosphatasia in osteoporosis clinic patients. | Austin Authors: | Ng, Elisabeth;Ashkar, Claudia;Seeman, Ego ;Schneider, Hans G;Nguyen, Hanh;Ebeling, Peter R;Sztal-Mazer, Shoshana | Affiliation: | Department of Endocrinology & Diabetes, Alfred Health, Melbourne, Australia. Department of Endocrinology & Diabetes, Alfred Health, Melbourne, Australia. Department of Medicine, University of Melbourne, Melbourne, Australia. Department of Endocrinology & Diabetes, Alfred Health, Melbourne, Australia. Endocrinology Department of Endocrinology, Monash Health, Clayton, Australia. |
Issue Date: | 2023 | Date: | 2022 | Publication information: | Osteoporosis International 2023; 34(2) | Abstract: | Low serum alkaline phosphatase (ALP) was found in 9% of patients attending an osteoporosis clinic, 0.6% of hospital patients, and 2/22 with an atypical femoral fracture. Hypophosphatasia was diagnosed in 3% of osteoporosis clinic patients with low ALP. Low ALP is a screening tool for hypophosphatasia, a condition potentially aggravated by antiresorptive therapy. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/31737 | DOI: | 10.1007/s00198-022-06597-3 | ORCID: | 0000-0001-6649-032X |
Journal: | Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA | PubMed URL: | 36434431 | ISSN: | 1433-2965 | Type: | Journal Article | Subjects: | Alkaline phosphatase Bisphosphonate Hypophosphatasemia Hypophosphatasia Osteoporosis |
Appears in Collections: | Journal articles |
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