Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/31665
Title: Leukocyte surface biomarkers implicate deficits of innate immunity in sporadic Alzheimer's disease.
Austin Authors: Huang, Xin;Li, Yihan;Fowler, Christopher;Doecke, James D;Lim, Yen Ying;Drysdale, Candace;Zhang, Vicky;Park, Keunha;Trounson, Brett;Pertile, Kelly;Rumble, Rebecca;Pickering, John W;Rissman, Robert A;Sarsoza, Floyd;Abdel-Latif, Sara;Lin, Yong;Doré, Vincent ;Villemagne, Victor L ;Rowe, Christopher C ;Fripp, Jurgen;Martins, Ralph;Wiley, James S;Maruff, Paul;Mintzer, Jacobo E;Masters, Colin L ;Gu, Ben J
Affiliation: The Florey Institute of Neuroscience and Mental Health
The Australian e-Health Research Centre, CSIRO, Brisbane, Queensland, Australia.
Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Victoria, Australia.
Department of Medicine, University of Otago, New Zealand and Department of Emergency Medicine, Christchurch Hospital, Christchurch, New Zealand.
Department of Neurosciences, University of California, San Diego, California, USA.
Alzheimer's Therapeutic Research Institute, University of Southern California, San Diego, California, USA.
National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.
The Australian e-Health Research Centre, CSIRO, Brisbane, Queensland, Australia.
Department of Molecular Imaging & Therapy, Austin Health, Melbourne, Australia, and Department of Medicine, the University of Melbourne, Melbourne, Australia.
Molecular Imaging and Therapy
The Australian e-Health Research Centre, CSIRO, Brisbane, Queensland, Australia.
Centre of Excellence for Alzheimer's Disease Research and Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia.
NeuroQuest, Inc., Medical University of South Carolina, South Carolina, USA.
Issue Date: May-2023
Date: 2022
Publication information: Alzheimer's & Dementia : the Journal of the Alzheimer's Association 2023-05; 19(5)
Abstract: Blood-based diagnostics and prognostics in sporadic Alzheimer's disease (AD) are important for identifying at-risk individuals for therapeutic interventions.
URI: https://ahro.austin.org.au/austinjspui/handle/1/31665
DOI: 10.1002/alz.12813
ORCID: 0000-0001-5500-4453
Journal: Alzheimer's & Dementia : the Journal of the Alzheimer's Association
PubMed URL: 36349985
ISSN: 1552-5279
Type: Journal Article
Subjects: Alzheimer's disease
CD11c
CD163
CD59
CD91
ROC curve
complement system
innate phagocytosis
leukocyte biomarker
peripheral immune response
receptor for advanced glycation end products (RAGE)
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