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Title: Oxygen targets and 6-month outcome after out of hospital cardiac arrest: a pre-planned sub-analysis of the targeted hypothermia versus targeted normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial.
Austin Authors: Robba, Chiara;Badenes, Rafael;Battaglini, Denise;Ball, Lorenzo;Sanfilippo, Filippo;Brunetti, Iole;Jakobsen, Janus Christian;Lilja, Gisela;Friberg, Hans;Wendel-Garcia, Pedro David;Young, Paul J;Eastwood, Glenn M ;Chew, Michelle S;Unden, Johan;Thomas, Matthew;Joannidis, Michael;Nichol, Alistair;Lundin, Andreas;Hollenberg, Jacob;Hammond, Naomi;Saxena, Manoj;Martin, Annborn;Solar, Miroslav;Taccone, Fabio Silvio;Dankiewicz, Josef;Nielsen, Niklas;Grejs, Anders Morten;Ebner, Florian;Pelosi, Paolo
Affiliation: Anesthesia and Critical Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, Genoa, Italy.
Department of Anesthesiology and Surgical-Trauma Intensive Care, Hospital Clínic Universitari de Valencia, Valencia, Spain.
Department of Anaesthesia and Intensive Care, A.O.U. "Policlinico-San Marco", Catania, Italy.
Copenhagen Trial Unit, Centre for Clinical Intervention Research, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Department of Clinical Sciences Lund, Neurology, Skåne University Hospital, Lund University, Getingevägen 4, 222 41, Lund, Malmö, Sweden.
Department of Clinical Sciences Lund, Anesthesia and Intensive Care, Lund University, Lund, Sweden.
Institute of Intensive Care Medicine, University Hospital of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Medical Research Institute of New Zealand, Wellington, New Zealand.
Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
Department of Anaesthesia and Intensive Care, Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck, Innsbruck, Austria.
Monash University, Melbourne, VIC, Australia.
Department of Anaesthesiology and Intensive Care Medicine, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, 423 45, Gothenburg, Sweden.
Department of Clinical Science and Education, Södersjukhuset, Centre for Resuscitation Science, Karolinska Institutet, Solna, Sweden.
Malcolm Fisher Department of Intensive Care, Royal North Shore Hospital, Critical Care Division, The George Institute for Global Health, Faculty of Medicine, UNSW Sydney, Sydney, Australia.
Intensive Care Unit, St George Hospital, Sydney, Australia.
Department of Clinical Medicine, Anaesthesiology and Intensive Care, Lund University, Lund, Sweden.
Department of Internal Medicine, Faculty of Medicine in Hradec Králové, Charles University, Hradec Králové, Czech Republic.
Department of Intensive Care Medicine, Université Libre de Bruxelles, Hopital Erasme, Brussels, Belgium.
Department of Clinical Sciences Lund, Cardiology, Skåne University Hospital, Lund University, Lund, Sweden.
Intensive Care
Department of Intensive Care Medicine, Aarhus University Hospital, Aarhus, Denmark.
Issue Date: 21-Oct-2022
Date: 2022
Publication information: Critical Care 2022
Abstract: Optimal oxygen targets in patients resuscitated after cardiac arrest are uncertain. The primary aim of this study was to describe the values of partial pressure of oxygen values (PaO2) and the episodes of hypoxemia and hyperoxemia occurring within the first 72 h of mechanical ventilation in out of hospital cardiac arrest (OHCA) patients. The secondary aim was to evaluate the association of PaO2 with patients' outcome.
DOI: 10.1186/s13054-022-04186-8
ORCID: 0000-0003-1628-3845
Journal: Critical Care
Start page: 323
PubMed URL: 36271410
ISSN: 1466-609X
Type: Journal Article
Subjects: Cardiac arrest
Neurological outcome
Out-of-Hospital Cardiac Arrest/complications
Appears in Collections:Journal articles

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