Oxygen targets and 6-month outcome after out of hospital cardiac arrest: a pre-planned sub-analysis of the targeted hypothermia versus targeted normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial.

Robba, Chiara; Badenes, Rafael; Battaglini, Denise; Ball, Lorenzo; Sanfilippo, Filippo; Brunetti, Iole; Jakobsen, Janus Christian; Lilja, Gisela; Friberg, Hans; Wendel-Garcia, Pedro David; Young, Paul J; Eastwood, Glenn M; Chew, Michelle S; Unden, Johan; Thomas, Matthew; Joannidis, Michael; Nichol, Alistair; Lundin, Andreas; Hollenberg, Jacob; Hammond, Naomi; Saxena, Manoj; Martin, Annborn; Solar, Miroslav; Taccone, Fabio Silvio; Dankiewicz, Josef; Nielsen, Niklas; Grejs, Anders Morten; Ebner, Florian; Pelosi, Paolo

doi:10.1186/s13054-022-04186-8

Title

Oxygen targets and 6-month outcome after out of hospital cardiac arrest: a pre-planned sub-analysis of the targeted hypothermia versus targeted normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial.

Publication Date

2022-10-21

Author(s)

Robba, Chiara

Badenes, Rafael

Battaglini, Denise

Ball, Lorenzo

Sanfilippo, Filippo

Brunetti, Iole

Jakobsen, Janus Christian

Lilja, Gisela

Friberg, Hans

Wendel-Garcia, Pedro David

Young, Paul J

Eastwood, Glenn M

Chew, Michelle S

Unden, Johan

Thomas, Matthew

Joannidis, Michael

Nichol, Alistair

Lundin, Andreas

Hollenberg, Jacob

Hammond, Naomi

Saxena, Manoj

Martin, Annborn

Solar, Miroslav

Taccone, Fabio Silvio

Dankiewicz, Josef

Nielsen, Niklas

Grejs, Anders Morten

Ebner, Florian

Pelosi, Paolo

Subject

Cardiac arrest

Hyperoxemia

Hypoxemia

Mortality

Neurological outcome

Type of document

Journal Article

OrcId

0000-0003-1628-3845

#PLACEHOLDER_PARENT_METADATA_VALUE#

DOI

10.1186/s13054-022-04186-8

Abstract

Optimal oxygen targets in patients resuscitated after cardiac arrest are uncertain. The primary aim of this study was to describe the values of partial pressure of oxygen values (PaO2) and the episodes of hypoxemia and hyperoxemia occurring within the first 72 h of mechanical ventilation in out of hospital cardiac arrest (OHCA) patients. The secondary aim was to evaluate the association of PaO2 with patients' outcome.

Link

link

Citation

Critical Care 2022

Jornal Title

Critical Care

ISSN

1466-609X

Austin Health

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