Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/31009
Title: What you need to know about: acute liver failure.
Austin Authors: Matthewman, Madeline Coxwell;Warrillow, Stephen J 
Affiliation: Intensive Care
Issue Date: 2-Sep-2022
Date: 2022
Publication information: British Journal of Hospital Medicine 2022; 83(9): 1-11
Abstract: Acute liver failure is a rare but important clinical syndrome, with a high mortality rate. Prompt recognition, appropriate management and early referral to a liver transplant centre can lead to good outcomes in these critically unwell patients. This article gives an overview of the key clinical challenges and optimal management of patients with acute liver failure. Acute liver failure is defined and a comprehensive list of aetiologies and suggested investigations is provided. The clinical challenges of sepsis, renal impairment, coagulopathy, hypoglycaemia, haemodynamic instability and cerebral oedema are discussed. Quadruple H therapy, a combination of therapies aimed to reduce cerebral oedema in acute liver failure, is described. A systemic guide to managing patients with acute liver failure is provided, as are indications for referral to a liver transplant centre.
URI: https://ahro.austin.org.au/austinjspui/handle/1/31009
DOI: 10.12968/hmed.2022.0051
Journal: British Journal of Hospital Medicine (London, England : 2005)
PubMed URL: 36193917
ISSN: 1750-8460
Type: Journal Article
Subjects: Acute liver failure
Fulminant liver failure
Intracranial hypertension
Liver transplantation
Quadruple H therapy
Appears in Collections:Journal articles

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