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https://ahro.austin.org.au/austinjspui/handle/1/30931| Title: | Diffuse large B-cell lymphoma: a consensus practice statement from the Australasian Lymphoma Alliance. | Austin Authors: | Wight, Joel C ;Hamad, Nada;Campbell, Belinda A;Ku, Matthew;Lee, Kenneth;Rose, Hannah;Armytage, Tasman;Latimer, Maya;Lee, Hui-Peng;Lee, Sze Ting ;Dickinson, Michael;Khor, Richard ;Verner, Emma | Affiliation: | Department of Haematology and Bone Marrow Transplantation, Townsville University Hospital, Townsville, Queensland, Australia.. Department of Haematology, Austin Health, Melbourne, Victoria, Australia.. School of Medicine, The University of Melbourne, Melbourne, Victoria, Australia.. School of Medicine, James Cook University, Townsville, Queensland, Australia.. Department of Haematology, St Vincent's Hospital, Sydney, New South Wales, Australia.. School of Medicine, University of Notre Dame, Sydney, New South Wales, Australia.. St Vincent's Clinical School, University of New South Wales, Sydney, New South Wales, Australia.. Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.. Department of Clinical Pathology, University of Melbourne, Melbourne, Victoria, Australia.. Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.. Department of Haematology, St Vincent's Hospital, Melbourne, Victoria, Australia.. School of Medicine, University of Sydney, Sydney, New South Wales, Australia.. Anatomical Pathology Department, NSW Health Pathology, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.. Department of Haematology, University Hospital, Geelong, Victoria, Australia.. School of Medicine, Deakin University, Geelong, Victoria, Australia.. Department of Haematology, Gosford Hospital, Gosford, New South Wales, Australia.. Department of Haematology, Canberra Hospital, Canberra, Australian Capital Territory, Australia.. Department of Haematology, Australian National University, Canberra, Australian Capital Territory, Australia.. Department of Haematology, Flinders Medical Centre, Adelaide, South Australia, Australia.. School of Medicine, The University of Melbourne, Melbourne, Victoria, Australia.. Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.. Department of Haematology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.. Clinical Haematology School of Medicine, University of Sydney, Sydney, New South Wales, Australia.. Department of Haematology, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.. |
Issue Date: | Sep-2022 | Date: | 2022 | Publication information: | Internal medicine journal 2022; 52(9): 1609-1623 | Abstract: | Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma subtype, accounting for 30-40% of lymphoma diagnoses. Although aggressive, cure is achievable in approximately 60% of cases with primary chemoimmunotherapy, and in a further substantial minority by salvage therapy and autologous stem cell transplantation. Despite promising activity in early phase clinical trials, no intensified or novel treatment regimen has improved outcomes over R-CHOP21 in randomised studies. However, there remain several areas of controversy including the most appropriate prognostic markers, central nervous system prophylaxis and the optimal treatment for patients with high-risk disease. This position statement presents an evidence-based synthesis of the literature for application in Australasian practice. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/30931 | DOI: | 10.1111/imj.15533 | ORCID: | https://orcid.org/0000-0002-3216-2392 https://orcid.org/0000-0001-7929-1450 https://orcid.org/0000-0002-9289-1335 https://orcid.org/0000-0001-8641-456X https://orcid.org/0000-0002-1492-5966 |
Journal: | Internal medicine journal | PubMed URL: | 34532916 | Type: | Journal Article | Subjects: | diagnosis diffuse large B-cell lymphoma management prognosis |
| Appears in Collections: | Journal articles |
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