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https://ahro.austin.org.au/austinjspui/handle/1/30778| Title: | Sex-bias in CD8+ T-cell stemness and exhaustion in cancer. | Austin Authors: | Hussain, Tabinda;Kallies, Axel;Vasanthakumar, Ajithkumar | Affiliation: | Olivia Newton-John Cancer Research Institute Peter Doherty Institute for Infection and Immunity Melbourne VIC Australia Department of Microbiology and Immunology University of Melbourne Melbourne VIC Australia La Trobe University Bundoora VIC Australia |
Issue Date: | 2022 | Date: | 2022 | Publication information: | Clinical & Translational Immunology 2022; 11(8): e1414 | Abstract: | This commentary article highlights two recently published studies, which for the first time revealed the immunological underpinnings of sex-bias in cancer incidence and mortality. These studies showed that the androgen receptor restrains anti-tumour immunity in males by repressing cytotoxic genes in CD8+ T cells. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/30778 | DOI: | 10.1002/cti2.1414 | ORCID: | https://orcid.org/0000-0002-1620-7781 | Journal: | Clinical & Translational Immunology | PubMed URL: | 36051310 | ISSN: | 2050-0068 | Type: | Journal Article |
| Appears in Collections: | Journal articles |
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