| Title |
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Sex-bias in CD8+ T-cell stemness and exhaustion in cancer. |
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| Publication Date |
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| Author(s) |
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Vasanthakumar, Ajithkumar |
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| Type of document |
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| OrcId |
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https://orcid.org/0000-0002-1620-7781 |
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| DOI |
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| Abstract |
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This commentary article highlights two recently published studies, which for the first time revealed the immunological underpinnings of sex-bias in cancer incidence and mortality. These studies showed that the androgen receptor restrains anti-tumour immunity in males by repressing cytotoxic genes in CD8+ T cells. |
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| Link |
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| Citation |
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Clinical & Translational Immunology 2022; 11(8): e1414 |
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| Jornal Title |
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Clinical & Translational Immunology |
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| ISSN |
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