Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/29989
Title: Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
Austin Authors: Trubetskoy, Vassily;Pardiñas, Antonio F;Qi, Ting;Panagiotaropoulou, Georgia;Awasthi, Swapnil;Bigdeli, Tim B;Bryois, Julien;Chen, Chia-Yen;Dennison, Charlotte A;Hall, Lynsey S;Lam, Max;Watanabe, Kyoko;Frei, Oleksandr;Ge, Tian;Harwood, Janet C;Koopmans, Frank;Magnusson, Sigurdur;Richards, Alexander L;Sidorenko, Julia;Wu, Yang;Zeng, Jian;Grove, Jakob;Kim, Minsoo;Li, Zhiqiang;Voloudakis, Georgios;Zhang, Wen;Adams, Mark;Agartz, Ingrid;Atkinson, Elizabeth G;Agerbo, Esben;Al Eissa, Mariam;Albus, Margot;Alexander, Madeline;Alizadeh, Behrooz Z;Alptekin, Köksal;Als, Thomas D;Amin, Farooq;Arolt, Volker;Arrojo, Manuel;Athanasiu, Lavinia;Azevedo, Maria Helena;Bacanu, Silviu A;Bass, Nicholas J;Begemann, Martin;Belliveau, Richard A;Bene, Judit;Benyamin, Beben;Bergen, Sarah E;Blasi, Giuseppe;Bobes, Julio;Bonassi, Stefano;Braun, Alice;Bressan, Rodrigo Affonseca;Bromet, Evelyn J;Bruggeman, Richard;Buckley, Peter F;Buckner, Randy L;Bybjerg-Grauholm, Jonas;Cahn, Wiepke;Cairns, Murray J;Calkins, Monica E;Carr, Vaughan J;Castle, David;Catts, Stanley V;Chambert, Kimberley D;Chan, Raymond C K;Chaumette, Boris;Cheng, Wei;Cheung, Eric F C;Chong, Siow Ann;Cohen, David;Consoli, Angèle;Cordeiro, Quirino;Costas, Javier;Curtis, Charles;Davidson, Michael;Davis, Kenneth L;de Haan, Lieuwe;Degenhardt, Franziska;DeLisi, Lynn E;Demontis, Ditte;Dickerson, Faith;Dikeos, Dimitris;Dinan, Timothy;Djurovic, Srdjan;Duan, Jubao;Ducci, Giuseppe;Dudbridge, Frank;Eriksson, Johan G;Fañanás, Lourdes;Faraone, Stephen V;Fiorentino, Alessia;Forstner, Andreas;Frank, Josef;Freimer, Nelson B;Fromer, Menachem;Frustaci, Alessandra;Gadelha, Ary;Genovese, Giulio;Gershon, Elliot S;Giannitelli, Marianna;Giegling, Ina;Giusti-Rodríguez, Paola;Godard, Stephanie;Goldstein, Jacqueline I;González Peñas, Javier;González-Pinto, Ana;Gopal, Srihari;Gratten, Jacob;Green, Michael F;Greenwood, Tiffany A;Guillin, Olivier;Gülöksüz, Sinan;Gur, Raquel E;Gur, Ruben C;Gutiérrez, Blanca;Hahn, Eric;Hakonarson, Hakon;Haroutunian, Vahram;Hartmann, Annette M;Harvey, Carol;Hayward, Caroline;Henskens, Frans A;Herms, Stefan;Hoffmann, Per;Howrigan, Daniel P;Ikeda, Masashi;Iyegbe, Conrad;Joa, Inge;Julià, Antonio;Kähler, Anna K;Kam-Thong, Tony;Kamatani, Yoichiro;Karachanak-Yankova, Sena;Kebir, Oussama;Keller, Matthew C;Kelly, Brian J;Khrunin, Andrey;Kim, Sung-Wan;Klovins, Janis;Kondratiev, Nikolay;Konte, Bettina;Kraft, Julia;Kubo, Michiaki;Kučinskas, Vaidutis;Kučinskiene, Zita Ausrele;Kusumawardhani, Agung;Kuzelova-Ptackova, Hana;Landi, Stefano;Lazzeroni, Laura C;Lee, Phil H;Legge, Sophie E;Lehrer, Douglas S;Lencer, Rebecca;Lerer, Bernard;Li, Miaoxin;Lieberman, Jeffrey;Light, Gregory A;Limborska, Svetlana;Liu, Chih-Min;Lönnqvist, Jouko;Loughland, Carmel M;Lubinski, Jan;Luykx, Jurjen J;Lynham, Amy;Macek, Milan;Mackinnon, Andrew;Magnusson, Patrik K E;Maher, Brion S;Maier, Wolfgang;Malaspina, Dolores;Mallet, Jacques;Marder, Stephen R;Marsal, Sara;Martin, Alicia R;Martorell, Lourdes;Mattheisen, Manuel;McCarley, Robert W;McDonald, Colm;McGrath, John J;Medeiros, Helena;Meier, Sandra;Melegh, Bela;Melle, Ingrid;Mesholam-Gately, Raquelle I;Metspalu, Andres;Michie, Patricia T;Milani, Lili;Milanova, Vihra;Mitjans, Marina;Molden, Espen;Molina, Esther;Molto, María Dolores;Mondelli, Valeria;Moreno, Carmen;Morley, Christopher P;Muntané, Gerard;Murphy, Kieran C;Myin-Germeys, Inez;Nenadić, Igor;Nestadt, Gerald;Nikitina-Zake, Liene;Noto, Cristiano;Nuechterlein, Keith H;O'Brien, Niamh Louise;O'Neill, F Anthony;Oh, Sang-Yun;Olincy, Ann;Ota, Vanessa Kiyomi;Pantelis, Christos;Papadimitriou, George N;Parellada, Mara;Paunio, Tiina;Pellegrino, Renata;Periyasamy, Sathish;Perkins, Diana O;Pfuhlmann, Bruno;Pietiläinen, Olli;Pimm, Jonathan;Porteous, David;Powell, John;Quattrone, Diego;Quested, Digby;Radant, Allen D;Rampino, Antonio;Rapaport, Mark H;Rautanen, Anna;Reichenberg, Abraham;Roe, Cheryl;Roffman, Joshua L;Roth, Julian;Rothermundt, Matthias;Rutten, Bart P F;Saker-Delye, Safaa;Salomaa, Veikko;Sanjuan, Julio;Santoro, Marcos Leite;Savitz, Adam;Schall, Ulrich;Scott, Rodney J;Seidman, Larry J;Sharp, Sally Isabel;Shi, Jianxin;Siever, Larry J;Sigurdsson, Engilbert;Sim, Kang;Skarabis, Nora;Slominsky, Petr;So, Hon-Cheong;Sobell, Janet L;Söderman, Erik;Stain, Helen J;Steen, Nils Eiel;Steixner-Kumar, Agnes A;Stögmann, Elisabeth;Stone, William S;Straub, Richard E;Streit, Fabian;Strengman, Eric;Stroup, T Scott;Subramaniam, Mythily;Sugar, Catherine A;Suvisaari, Jaana;Svrakic, Dragan M;Swerdlow, Neal R;Szatkiewicz, Jin P;Ta, Thi Minh Tam;Takahashi, Atsushi;Terao, Chikashi;Thibaut, Florence;Toncheva, Draga;Tooney, Paul A;Torretta, Silvia;Tosato, Sarah;Tura, Gian Battista;Turetsky, Bruce I;Üçok, Alp;Vaaler, Arne;van Amelsvoort, Therese;van Winkel, Ruud;Veijola, Juha;Waddington, John;Walter, Henrik;Waterreus, Anna;Webb, Bradley T;Weiser, Mark;Williams, Nigel M;Witt, Stephanie H;Wormley, Brandon K;Wu, Jing Qin;Xu, Zhida;Yolken, Robert;Zai, Clement C;Zhou, Wei;Zhu, Feng;Zimprich, Fritz;Atbaşoğlu, Eşref Cem;Ayub, Muhammad;Benner, Christian;Bertolino, Alessandro;Black, Donald W;Bray, Nicholas J;Breen, Gerome;Buccola, Nancy G;Byerley, William F;Chen, Wei J;Cloninger, C Robert;Crespo-Facorro, Benedicto;Donohoe, Gary;Freedman, Robert;Galletly, Cherrie;Gandal, Michael J;Gennarelli, Massimo;Hougaard, David M;Hwu, Hai-Gwo;Jablensky, Assen V;McCarroll, Steven A;Moran, Jennifer L;Mors, Ole;Mortensen, Preben B;Müller-Myhsok, Bertram;Neil, Amanda L;Nordentoft, Merete;Pato, Michele T;Petryshen, Tracey L;Pirinen, Matti;Pulver, Ann E;Schulze, Thomas G;Silverman, Jeremy M;Smoller, Jordan W;Stahl, Eli A;Tsuang, Debby W;Vilella, Elisabet;Wang, Shi-Heng;Xu, Shuhua;Adolfsson, Rolf;Arango, Celso;Baune, Bernhard T;Belangero, Sintia Iole;Børglum, Anders D;Braff, David;Bramon, Elvira;Buxbaum, Joseph D;Campion, Dominique;Cervilla, Jorge A;Cichon, Sven;Collier, David A;Corvin, Aiden;Curtis, David;Forti, Marta Di;Domenici, Enrico;Ehrenreich, Hannelore;Escott-Price, Valentina;Esko, Tõnu;Fanous, Ayman H;Gareeva, Anna;Gawlik, Micha;Gejman, Pablo V;Gill, Michael;Glatt, Stephen J;Golimbet, Vera;Hong, Kyung Sue;Hultman, Christina M;Hyman, Steven E;Iwata, Nakao;Jönsson, Erik G;Kahn, René S;Kennedy, James L;Khusnutdinova, Elza;Kirov, George;Knowles, James A;Krebs, Marie-Odile;Laurent-Levinson, Claudine;Lee, Jimmy;Lencz, Todd;Levinson, Douglas F;Li, Qingqin S;Liu, Jianjun;Malhotra, Anil K;Malhotra, Dheeraj;McIntosh, Andrew;McQuillin, Andrew;Menezes, Paulo R;Morgan, Vera A;Morris, Derek W;Mowry, Bryan J;Murray, Robin M;Nimgaonkar, Vishwajit;Nöthen, Markus M;Ophoff, Roel A;Paciga, Sara A;Palotie, Aarno;Pato, Carlos N;Qin, Shengying;Rietschel, Marcella;Riley, Brien P;Rivera, Margarita;Rujescu, Dan;Saka, Meram C;Sanders, Alan R;Schwab, Sibylle G;Serretti, Alessandro;Sham, Pak C;Shi, Yongyong;St Clair, David;Stefánsson, Hreinn;Stefansson, Kari;Tsuang, Ming T;van Os, Jim;Vawter, Marquis P;Weinberger, Daniel R;Werge, Thomas;Wildenauer, Dieter B;Yu, Xin;Yue, Weihua;Holmans, Peter A;Pocklington, Andrew J;Roussos, Panos;Vassos, Evangelos;Verhage, Matthijs;Visscher, Peter M;Yang, Jian;Posthuma, Danielle;Andreassen, Ole A;Kendler, Kenneth S;Owen, Michael J;Wray, Naomi R;Daly, Mark J;Huang, Hailiang;Neale, Benjamin M;Sullivan, Patrick F;Ripke, Stephan;Walters, James T R;O'Donovan, Michael C
Affiliation: Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK
Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany..
School of Psychology, University of Newcastle, Newcastle, New South Wales, Australia
, Sydney, New South Wales, Australia
Neuroscience Research Australia
Department of Psychiatry, Monash University, Melbourne, Victoria, Australia
School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia
Centre for Brain and Mental Health Research, University of Newcastle, Newcastle, New South Wales, Australia
School of Medicine, University of Queensland, Herston, Queensland, Australia
Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia
St Vincent's Hospital, Melbourne, Victoria, Australia
Department of Psychiatry, University of Melbourne, Parkville, Victoria, Australia
Division of Molecular Medicine, NSW Health Pathology North, Newcastle, New South Wales, Australia
Hunter Medical Research Institute, Newcastle, New South Wales, Australia
School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia
School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia
Queensland Centre for Mental Health Research, University of Queensland, Brisbane, Queensland, Australia
Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia
School of Life Sciences, Westlake University, Hangzhou, China..
Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia
Oxford Health NHS Foundation Trust, Oxford, UK
University Medical Center Utrecht, Department of Psychiatry, Utrecht, The Netherlands..
Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK
Dementia Research Institute, Cardiff University, Cardiff, UK
Centre for Psychiatry, Queen Mary University London, London, UK
UCL Genetics Institute, University College London, London, UK
Eli Lilly and Company, Windlesham, UK
Division of Psychiatry, Department of Mental Health Neuroscience, University College London, London, UK
Max Planck Institute of Psychiatry, Munich, Germany.. Munich Cluster for Systems Neurology, Munich, Germany.. Department of Health Data Science, University of Liverpool, Liverpool, UK
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands..
South London and Maudsley NHS Mental Health Foundation Trust, London, UK
Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK
Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK
Barnet, Enfield and Haringey Mental Health NHS Trust, St Ann's Hospital, London, UK
Department of Health Sciences, University of Leicester, Leicester, UK
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK
Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK
Department of Psychiatry, University of Oxford, Oxford, UK
Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK
TIPS - Network for Clinical Research in Psychosis, Stavanger University Hospital, Stavanger, Norway..
Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK
MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK
Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK
Centre for Public Health, Institute of Clinical Sciences, Queen's University Belfast, Belfast, UK
MRC Human Genetics Unit, University of Edinburgh, Institute of Genetics and Cancer, Western General Hospital, Edinburgh, UK
School of Social and Health Sciences, Leeds Trinity University, Leeds, UK
Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.. Analytic and Translational Genetics Unit, Department of Medicine, Department of Neurology and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
Department of Psychiatry, Erasmus University Medical Center, Rotterdam, The Netherlands..
Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, CA, USA
Department of Cell Biology, State University of New York, Downstate Health Sciences University, New York, NY, USA
Department of Psychiatry and Zilkha Neurogenetics Institute, Keck School of Medicine at University of Southern California, Los Angeles, CA, USA
University Medical Center Utrecht, Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands.. Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.. Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University, Baltimore, MD, USA
Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany.. Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA
VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA
Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, USA
Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
Research Division, Institute of Mental Health, Singapore, Republic of Singapore.. Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA
Mental Illness Research, Education, and Clinical Center (VISN 2 South), James J. Peters VA Medical Center, New York, NY, USA
Department of Psychiatry and Human Behavior, School of Medicine, University of California Irvine, Irvine, CA, USA
Institute of Genomic Medicine, University of California San Diego, La Jolla, CA, USA
Center for Behavioral Genomics, Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.. Department of Genetics, University of North Carolina, Chapel Hill, NC, USA
Department of Medicine, Harvard Medical School, Boston, MA, USA
Early Clinical Development, Pfizer Worldwide Research and Development, Groton, CT, USA
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
Department of Psychiatry, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA
Institute of Behavioral Science, Feinstein Institutes for Medical Research, Manhasset, NY, USA
Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA
Psychiatric Genetic Epidemiology and Neurobiology Laboratory (PsychGENe lab), Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA
Banner-University Medical Center, Phoenix, AZ, USA
Department of Psychiatry, Phoenix VA Healthcare System, Phoenix, AZ, USA
Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.. Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA
Regeneron Genetics Center, Orange, CA, USA
Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA
Stanley Neurovirology Laboratory, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Rutgers University, New Jersey Medical School, Newark, NJ, USA
Rutgers University, Robert Wood Johnson Medical School, New Brunswick, NJ, USA
Department of Psychiatry, University of California San Francisco, San Francisco, CA, USA
School of Nursing, Louisiana State University Health Sciences Center, New Orleans, LA, USA
Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA
Department of Psychiatry, School of Medicine, Ankara University, Ankara, Turkey..
Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
SUNY Upstate Medical University, Syracuse, NY, USA
Huntsman Mental Health Institute, Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT, USA
VA Puget Sound Health Care System, Seattle, WA, USA
Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
Department of Psychiatry, Washington University, St Louis, MO, USA
Department of Biostatistics, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA
Lieber Institute for Brain Development, Baltimore, MD, USA
Massachusetts Mental Health Center, Boston, MA, USA
Harvard Medical School Department of Psychiatry at Beth Israel Deaconess Medical Center, Boston, MA, USA
James J. Peters VA Medical Center, Bronx, NY, USA
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Semel Institute for Neurosciene, University of California Los Angeles, Los Angeles, CA, USA
Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland..
Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA
Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA
Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Psychiatry, University of Colorado Denver, Aurora, CO, USA
Departments of Public Health and Preventive Medicine, Family Medicine, and Psychiatry and Behavioral Sciences, State University of New York, Upstate Medical University, Syracuse, NY, USA
Massachusetts Mental Health Center Public Psychiatry Division of the Beth Israel Deaconess Medical Center, Boston, MA, USA
Computational Research Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA
Department of Statistics and Applied Probability, University of California at Santa Barbara, Santa Barbara, CA, USA
Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
College of Medicine, SUNY Downstate Health Sciences University, New York, NY, USA
Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
VA Boston Health Care System, Brockton, MA, USA
Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
VISN 22, Mental Illness Research, Education and Clinical Center (MIRECC), VA San Diego Healthcare System, San Diego, CA, USA
Department of Psychiatry, Columbia University, New York, NY, USA
Department of Psychiatry, Wright State University, Dayton, OH, USA
Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry and Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Institute for Behavioural Genetics, University of Colorado Boulder, Boulder, CO, USA
Department of Biomedical Data Science, Stanford University, Stanford, CA, USA
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA
Children's Hospital of Philadelphia, Leonard Madlyn Abramson Research Center, Philadelphia, PA, USA
Broad Institute of MIT and Harvard, Cambridge, MA, USA
Mental Illness Research Clinical and Education Center (MIRECC), JJ Peters VA Medical Center, New York, NY, USA
Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Neuroscience Therapeutic Area, Janssen Research and Development, Titusville, NJ, USA
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.. Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA
Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
Departments of Psychiatry and Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA
Department of Psychiatry and Behavioral Neurosciences, The University of Chicago, Chicago, IL, USA
Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL, USA
Sheppard Pratt Health System, Baltimore, MD, USA
Cambridge Health Alliance, Cambridge, MA, USA
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Genetics, University of North Carolina, Chapel Hill, NC, USA
Departments of Psychiatry and Human Genetics, University of Chicago, Chicago, IL, USA
Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Genetics and Genomic Sciences and Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Psychiatry, Pamela Sklar Division of Psychiatric Genomics, Friedman Brain Institute, Department of Genetics and Genomic Science and Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Computer Science, University of North Carolina, Chapel Hill, NC, USA
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
Department of Psychology, Harvard University, Cambridge, MA, USA
Health Science Center, University of Tennessee, Memphis, TN, USA
Department of Psychiatry and Behavioural Health, Stony Brook University, Stony Brook, NY, USA
Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA
Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA
Center for Depression, Anxiety and Stress Research, McLean Hospital, Belmont, MA, USA
Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA
Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA
Biogen, Cambridge, MA, USA
Department of Psychiatry, Veterans Affairs New York Harbor Healthcare System, New York, NY, USA
Institute for Genomic Health, SUNY Downstate Medical Center, New York, NY, USA
Department of Psychiatry and the Behavioral Sciences, SUNY Downstate Medical Center, New York, NY, USA
Department of Psychiatry, Semel Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
School of Life Sciences, Westlake University, Hangzhou, China.. Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China..
School of Psychiatry and Clinical Neurosciences, University of Western Australia
Department of Psychiatry, University of Münster, Münster, Germany..
Northern Adelaide Local Health Network, Adelaide, South Australia
Ramsay Health Care (SA) Mental Health, Adelaide, South Australia
Discipline of Psychiatry, Adelaide Medical School, University of Adelaide, Adelaide, South Australia
Priority Centre for Brain and Mental Health Research, University of Newcastle, Mater Hospital, McAuley Centre, Newcastle, New South Wales, Australia
Department of Psychiatry, Melbourne Medical School, University of Melbourne, Parkville, Victoria, Australia
The Florey Institute of Neuroscience and Mental Health
Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Melbourne, Victoria, Australia
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Brisbane, Queensland, Australia
National Centre for Register-based Research, Aarhus University, Aarhus, Denmark.. Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia
Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia
n Health and Medical Research Institute, Adelaide, South Australia
South Australia
UniSA Allied Health and Human Performance, University of South Australia
, Adelaide, South Australia
Cancer Research Institute, University of South Australia
n Centre for Precision Health, University of South Australia
Australia
Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia
Black Dog Institute, University of New South Wales, Randwick, New South Wales, Australia
Mater Research Institute, University of Queensland, Brisbane, Queensland, Australia
Hunter New England Health and University of Newcastle, Newcastle, New South Wales, Australia
NorthWestern Mental Health, Melbourne, Victoria, Australia
Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia
Illawarra Health and Medical Research Institute, Wollongong, New South Wales, Australia
Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, New South Wales, Australia
Centre for Clinical Research in Neuropsychiatry, University of Western Australia
, Australia
, Perth, Western Australia
Neuropsychiatric Epidemiology Research Unit, School of Population and Global Health, University of Western Australia
Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany..
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden..
Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands..
NORMENT Centre, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway.. Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.. Center for Bioinformatics, Department of Informatics, University of Oslo, Oslo, Norway..
Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Faculty of Science, Amsterdam Neuroscience, Vrije Universiteit, Amsterdam, The Netherlands..
deCODE Genetics, Amgen, Reykjavik, Iceland..
The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.. Department of Biomedicine and Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.. Center for Genomics and Personalized Medicine, Aarhus, Denmark..
Affiliated Hospital of Qingdao University and Biomedical Sciences Institute of Qingdao University (Qingdao Branch of SJTU Bio-X Institutes), Qingdao University, Qingdao, China.. Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Collaborative Innovation Center for Brain Science, Shanghai Jiao Tong University, Shanghai, China..
NORMENT Centre, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway.. Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.. Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm Health Care Services, Stockholm Region, Stockholm, Sweden..
The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.. National Centre for Register-based Research, Aarhus University, Aarhus, Denmark..
Comedicum Lindwurmhof, Munich, Germany..
University Medical Center Groningen, University Center for Psychiatry, Rob Giel Research Center, University of Groningen, Groningen, The Netherlands.. Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands..
Department of Psychiatry, Dokuz Eylül University School of Medicine, Izmir, Turkey.. Department of Neuroscience, Dokuz Eylül University Graduate School of Health Sciences, Izmir, Turkey..
The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.. Department of Biomedicine and Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.. Center for Genomics and Personalized Medicine, Aarhus, Denmark..
Department of Psychiatry, University of Münster, Münster, Germany..
Servizo de Psiquiatría, Complexo Hospitalario Universitario de Santiago de Compostela, Servizo Galego de Saúde (SERGAS), Santiago de Compostela, Spain..
NORMENT Centre, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway.. Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway..
Institute of Medical Psychology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal..
Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany..
Department of Medical Genetics, Medical School, University of Pécs, Pécs, Hungary..
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden..
Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari 'Aldo Moro', Bari, Italy..
Área de Psiquiatría-Universidad de Oviedo, Hospital Universitario Central de Asturias (HUCA), Asturias, Spain.. Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Asturias, Spain.. Centro de Investigación Biomédica en Red de Salud Mental, Oviedo, Asturias, Spain..
Unit of Clinical and Molecular Epidemiology, IRCCS San Raffaele Roma and San Raffaele University, Rome, Italy..
Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany..
Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.. Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil..
University Medical Center Groningen, University Center for Psychiatry, Rob Giel Research Center, University of Groningen, Groningen, The Netherlands.. Department of Clinical and Developmental Neuropsychology, University of Groningen, Groningen, The Netherlands..
The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.. Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark..
University Medical Center Utrecht, Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands.. Altrecht, General Menthal Health Care, Utrecht, The Netherlands..
Institute of Psychology, Chinese Academy of Science, Beijing, China.. Department of Psychology, University of Chinese Academy of Sciences, Beijing, China..
INSERM U1266, Institute of Psychiatry and Neuroscience of Paris, Université de Paris, GHU Paris Psychiatrie & Neurosciences, Paris, France.. Department of Psychiatry, McGill University, Montreal, Québec, Canada..
Castle Peak Hospital, Hong Kong, China..
Research Division, Institute of Mental Health, Singapore, Republic of Singapore.. Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Republic of Singapore..
Faculté de Médecine Sorbonne Université, Groupe de Recherche Clinique no. 15 - Troubles Psychiatriques et Développement (PSYDEV), Department of Child and Adolescent Psychiatry, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France.. Centre de Référence des Maladies Rares à Expression Psychiatrique, Department of Child and Adolescent Psychiatry, AP-HP Sorbonne Université, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France.. Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR7222, Faculté des Sciences et Ingénierie, Sorbonne Université, Paris, France..
Faculté de Médecine Sorbonne Université, Groupe de Recherche Clinique no. 15 - Troubles Psychiatriques et Développement (PSYDEV), Department of Child and Adolescent Psychiatry, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France.. Centre de Référence des Maladies Rares à Expression Psychiatrique, Department of Child and Adolescent Psychiatry, AP-HP Sorbonne Université, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France..
Department of Psychiatry, Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil..
Instituto de Investigación Sanitaria (IDIS) de Santiago de Compostela, Complexo Hospitalario Universitario de Santiago de Compostela (CHUS), Servizo Galego de Saúde (SERGAS), Santiago de Compostela, Spain..
University of Nicosia Medical School, Nicosia, Cyprus..
Department of Psychiatry, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.. Arkin, Institute for Mental Health, Amsterdam, The Netherlands..
Institute of Human Genetics, University of Bonn, Bonn, Germany..
The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.. Department of Biomedicine and Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.. Center for Genomics and Personalized Medicine, Aarhus, Denmark..
First Department of Psychiatry, Medical School, National and Kapodistrian University of Athens, Eginition Hospital, Athens, Greece..
Department of Psychiatry and Neurobehavioural Sciences, University College Cork, Cork, Ireland.. APC Microbiome Ireland, University College Cork, Cork, Ireland..
NORMENT Centre, Department of Clinical Science, University of Bergen, Bergen, Norway.. Department of Medical Genetics, Oslo University Hospital, Oslo, Norway..
Department of Mental Health, ASL Rome 1, Rome, Italy..
Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.. Folkhälsan Research Center, Helsinki, Finland.. Department of Obstetrics and Gynecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore..
Department of Evolutionary Biology, Ecology and Environmental Sciences, Faculty of Biology, University of Barcelona, Barcelona, Spain.. Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain..
Institute of Human Genetics, University of Bonn, Bonn, Germany.. Centre for Human Genetics, University of Marburg, Marburg, Germany..
Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany..
Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.. Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil..
Faculté de Médecine Sorbonne Université, Groupe de Recherche Clinique no. 15 - Troubles Psychiatriques et Développement (PSYDEV), Department of Child and Adolescent Psychiatry, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France.. Centre de Référence des Maladies Rares à Expression Psychiatrique, Department of Child and Adolescent Psychiatry, AP-HP Sorbonne Université, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France..
Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria..
Departments of Psychiatry and Human and Molecular Genetics, INSERM, Institut de Myologie, Hôpital de la Pitiè-Salpêtrière, Paris, France..
Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.. Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, IiSGM, Madrid, Spain..
Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.. BIOARABA Health Research Institute, OSI Araba, University Hospital, University of the Basque Country, Vitoria, Spain..
INSERM, Rouen, France.. Centre Hospitalier du Rouvray, Rouen, France.. UFR Santé, Université de Rouen Normandie, Rouen, France..
Department of Psychiatry, Faculty of Medicine and Biomedical Research Centre (CIBM), University of Granada, Granada, Spain..
Department of Psychiatry, Charité - Universitätsmedizin, Berlin, Germany..
Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria..
Division of Medical Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland..
Department of Psychiatry, Fujita Health University School of Medicine, Toyoake Aichi, Japan..
Regional Centre for Clinical Research in Psychosis, Department of Psychiatry, Stavanger University Hospital, Stavanger, Norway..
Rheumatology Research Group, Vall d'Hebron Research Institute, Barcelona, Spain..
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden..
Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffman-La Roche, Basel, Switzerland..
Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.. Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan..
Department of Medical Genetics, Medical University, Sofia, Bulgaria.. Department of Genetics, Faculty of Biology, Sofia University "St. Kliment Ohridski", Sofia, Bulgaria..
INSERM U1266, Institute of Psychiatry and Neuroscience of Paris, Université de Paris, GHU Paris Psychiatrie & Neurosciences, Paris, France..
Institute of Molecular Genetics of National Research Centre "Kurchatov Institute", Moscow, Russia..
Department of Psychiatry, Chonnam National University Medical School, Gwangju, Korea..
Latvian Biomedical Research and Study Centre, Riga, Latvia..
Mental Health Research Center, Moscow, Russian Federation..
Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria..
Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany.. Berlin School of Mind and Brain, Humboldt-Universität zu Berlin, Berlin, Germany..
RIKEN Center for Integrative Medical Sciences, Yokohama, Japan..
Faculty of Medicine, Vilnius University, Vilnius, Lithuania..
Psychiatry Department, University of Indonesia - Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia..
Department of Psychiatry, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic..
Dipartimento di Biologia, Universita' di Pisa, Pisa, Italy..
Department of Psychiatry, University of Münster, Münster, Germany..
Department of Psychiatry, Hadassah-Hebrew University Medical Center, Jerusalem, Israel..
Zhongshan School of Medicine and Key Laboratory of Tropical Diseases Control (SYSU), Sun Yat-sen University, Guangzhou, China..
Institute of Molecular Genetics of National Research Centre "Kurchatov Institute", Moscow, Russia..
Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan.. Neurobiology and Cognitive Science Center, National Taiwan University, Taipei, Taiwan..
Mental Health Unit, Department of Public Health Solutions, National Institute for Health and Welfare, Helsinki, Finland.. Department of Psychiatry, University of Helsinki, Helsinki, Finland..
Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University in Szczecin, Szczecin, Poland..
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.. Department of Psychiatry, UMC Utrecht Brain Center, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.. Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.. Second Opinion Outpatient Clinic, GGNet Mental Health, Warnsveld, The Netherlands..
Department of Biology and Medical Genetics, 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic..
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden..
Department for Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany..
Asfalia Biologics, iPEPS-ICM, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France..
Rheumatology Research Group, Vall d'Hebron Research Institute, Barcelona, Spain..
Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain..
Department of Biomedicine and Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.. Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.. Department of Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.. Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany..
Centre for Neuroimaging, Cognition and Genomics (NICOG), National University of Ireland Galway, Galway, Ireland..
Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.. Department of Biomedicine, Aarhus University, Aarhus, Denmark..
Department of Medical Genetics, University of Pécs, School of Medicine, Pécs, Hungary..
NORMENT Centre, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway.. Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway..
Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia..
Psychiatric Clinic, Alexandrovska University Hospital, Sofia, Bulgaria..
Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany..
Department of Pharmacy, University of Oslo, Oslo, Norway.. Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway..
Department of Nursing, Faculty of Health Sciences and Biomedical Research Centre (CIBM), University of Granada, Granada, Spain..
Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.. Department of Genetics, Faculty of Biological Sciences, Universidad de Valencia, Valencia, Spain.. Biomedical Research Institute INCLIVA, Valencia, Spain..
Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.. Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, IiSGM, Madrid, Spain..
Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain.. Institut de Biologia Evolutiva (UPF-CSIC), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, PRBB, Barcelona, Spain..
Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland..
Department for Neurosciences, Center for Contextual Psychiatry, KU Leuven, Leuven, Belgium..
Cognitive Neuropsychiatry Laboratory, Department of Psychiatry and Psychotherapy, Philipps Universität Marburg, Marburg, Germany.. Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany..
Latvian Biomedical Research and Study Centre, Riga, Latvia..
Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.. Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil..
Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil.. Department of Morphology and Genetics, Laboratorio de Genetica, Universidade Federal de São Paulo, São Paulo, Brazil..
First Department of Psychiatry, Medical School, National and Kapodistrian University of Athens, Eginition Hospital, Athens, Greece..
Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.. Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, IiSGM, Madrid, Spain..
Department of Public Health Solutions, Genomics and Biomarkers Unit, National Institute for Health and Welfare, Helsinki, Finland.. Department of Psychiatry and SleepWell Research Program, Faculty of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland..
Clinic of Psychiatry and Psychotherapy, Weißer Hirsch, Dresden, Germany..
Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari 'Aldo Moro', Bari, Italy..
Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffman-La Roche, Basel, Switzerland..
Department of Psychiatry, Psychosomatics and Psychotherapy, Julius-Maximilians-Universität Würzburg, Würzburg, Germany..
Department of Psychiatry, University of Münster, Münster, Germany..
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands..
Généthon, Evry, France..
THL-Finnish Institute for Health and Welfare, Helsinki, Finland..
Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.. Biomedical Research Institute INCLIVA, Valencia, Spain.. Department of Psychiatry, School of Medicine, University of Valencia, Hospital Clínico Universitario de Valencia, Valencia, Spain..
Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil.. Department of Morphology and Genetics, Laboratorio de Genetica, Universidade Federal de São Paulo, São Paulo, Brazil..
Faculty of Medicine, University of Iceland, Reykjavik, Iceland.. Department of Psychiatry, Landspitali University Hospital, Reykjavik, Iceland..
West Region, Institute of Mental Health, Singapore, Singapore.. Yoo Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.. Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore..
Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany..
Institute of Molecular Genetics of National Research Centre "Kurchatov Institute", Moscow, Russia..
School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.. Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong, China..
Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm Health Care Services, Stockholm Region, Stockholm, Sweden..
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.. NORMENT Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway..
Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany..
Department of Neurology, Medical University of Vienna, Vienna, Austria..
Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany..
Department of Medical Genetics, University Medical Centre Utrecht, Utrecht, The Netherlands..
Research Division, Institute of Mental Health, Singapore, Republic of Singapore.. Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Republic of Singapore..
THL-Finnish Institute for Health and Welfare, Helsinki, Finland..
Department of Psychiatry, Charité - Universitätsmedizin Berlin, Berlin, Germany.. Berlin Institute of Health (BIH), Berlin, Germany..
Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan..
Université de Paris, Faculté de Médecine, Hôpital Cochin-Tarnier, Paris, France.. INSERM U1266, Institut de Psychiatrie et de Neurosciences, Paris, France..
Department of Medical Genetics, Medical University, Sofia, Bulgaria.. Bulgarian Academy of Science, Sofia, Bulgaria..
Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari 'Aldo Moro', Bari, Italy..
Department of Neuroscience, Biomedicine and Movement Sciences, Section of Psychiatry, University of Verona, Verona, Italy..
Psychiatry Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy..
Department of Psychiatry, Faculty of Medicine, Istanbul University, Istanbul, Turkey..
Division of Mental Health, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway.. Department of Mental Health, Norwegian University of Science and Technology, Trondheim, Norway..
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.. Department of Neurosciences, Center for Clinical Psychiatry, KU Leuven, Leuven, Belgium..
Department of Psychiatry, Research Unit of Clinical Neuroscience, University of Oulu, Oulu, Finland.. Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland..
Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland..
Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany..
Sheba Medical Center, Tel Hashomer, Israel..
Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany..
Department of Psychiatry, GGz Centraal, Utrecht, The Netherlands..
Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.. Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada..
Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Collaborative Innovation Center for Brain Science, Shanghai Jiao Tong University, Shanghai, China..
Department of Psychiatry, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.. Center for Translational Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China..
Department of Neurology, Medical University of Vienna, Vienna, Austria..
Department of Psychiatry, Queens University Kingston, Kingston, Ontario, Canada..
Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland..
Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari 'Aldo Moro', Bari, Italy..
Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan Town, Taiwan.. Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan..
University of Sevilla, CIBERSAM IBiS, Seville, Spain.. Hospital Universitario Virgen del Rocio, Department of Psychiatry, Universidad del Sevilla, Seville, Spain..
Centre for Neuroimaging, Cognition and Genomics (NICOG), National University of Ireland Galway, Galway, Ireland..
Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.. Genetic Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy..
The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.. Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark..
Neurobiology and Cognitive Science Center, National Taiwan University, Taipei, Taiwan.. Department of Psychiatry, College of Medicine and National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan..
The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.. Psychosis Research Unit, Aarhus University Hospital, Aarhus, Denmark..
The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.. National Centre for Register-based Research, Aarhus University, Aarhus, Denmark..
The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.. Mental Health Services in the Capital Region of Denmark, Mental Health Center Copenhagen, University of Copenhagen, Copenhagen, Denmark..
Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.. Department of Mathematics and Statistics, University of Helsinki, Helsinki, Finland.. Department of Public Health, University of Helsinki, Helsinki, Finland..
Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain..
College of Public Health, China Medical University, Taichung, Taiwan..
State Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center of Genetics and Development, Human Phenome Institute, School of Life Sciences, Fudan University, Shanghai, China.. School of Life Science and Technology, ShanghaiTech University, Shanghai, China.. Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, China..
Department of Clinical Sciences, Psychiatry, Umeå University, Umeå, Sweden..
Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.. Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, IiSGM, Madrid, Spain..
Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil.. Department of Morphology and Genetics, Laboratorio de Genetica, Universidade Federal de São Paulo, São Paulo, Brazil..
The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.. Department of Biomedicine and Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.. Center for Genomics and Personalized Medicine, Aarhus, Denmark..
INSERM, Rouen, France.. Centre Hospitalier du Rouvray, Rouen, France..
Department of Psychiatry, San Cecilio University Hospital, University of Granada, Granada, Spain..
Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.. Department of Biomedicine, University of Basel, Basel, Switzerland.. Institute of Neuroscience and Medicine (INM-1), Research Center Juelich, Juelich, Germany..
Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland..
Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy..
Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany..
Department of Human Molecular Genetics of the Institute of Biochemistry and Genetics of the Ufa Federal Research Center of the Russian Academy of Sciences (IBG UFRC RAS), Ufa, Russia.. Federal State Educational Institution of Highest Education Bashkir State Medical University of Public Health Ministry of Russian Federation (BSMU), Ufa, Russia..
Department of Psychiatry, Psychosomatics and Psychotherapy, Julius-Maximilians-Universität Würzburg, Würzburg, Germany..
Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland..
Mental Health Research Center, Moscow, Russian Federation..
Department of Psychiatry, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea..
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden..
Department of Psychiatry, Fujita Health University School of Medicine, Toyoake Aichi, Japan..
Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm Health Care Services, Stockholm Region, Stockholm, Sweden.. NORMENT Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway..
Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.. Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada..
Department of Human Molecular Genetics of the Institute of Biochemistry and Genetics of the Ufa Federal Research Center of the Russian Academy of Sciences (IBG UFRC RAS), Ufa, Russia.. Federal State Educational Institution of Highest Education Bashkir State Medical University of Public Health Ministry of Russian Federation (BSMU), Ufa, Russia..
INSERM U1266, Institute of Psychiatry and Neuroscience of Paris, Université de Paris, GHU Paris Psychiatrie & Neurosciences, Paris, France..
Faculté de Médecine Sorbonne Université, Groupe de Recherche Clinique no. 15 - Troubles Psychiatriques et Développement (PSYDEV), Department of Child and Adolescent Psychiatry, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France.. Centre de Référence des Maladies Rares à Expression Psychiatrique, Department of Child and Adolescent Psychiatry, AP-HP Sorbonne Université, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France..
Department of Psychosis, Institute of Mental Health, Singapore, Singapore.. Neuroscience and Mental Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore..
Human Genetics, Genome Institute of Singapore, A*STAR, Singapore, Singapore.. Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore..
Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffman-La Roche, Basel, Switzerland..
Department of Preventative Medicine, Faculdade de Medicina FMUSP, University of São Paulo, São Paulo, Brazil..
Centre for Neuroimaging, Cognition and Genomics (NICOG), National University of Ireland Galway, Galway, Ireland..
Institute of Human Genetics, University of Bonn, Bonn, Germany..
Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Collaborative Innovation Center for Brain Science, Shanghai Jiao Tong University, Shanghai, China.. Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China..
Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany..
Department of Biochemistry and Molecular Biology II, Faculty of Pharmacy, University of Granada, Granada, Spain.. Institute of Neurosciences, Biomedical Research Center (CIBM), University of Granada, Granada, Spain..
Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria..
Department of Psychiatry, School of Medicine, Ankara University, Ankara, Turkey..
Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy..
Centre for PanorOmic Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.. State Key Laboratory of Brain and Cognitive Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.. Department of Psychiatry, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China..
Affiliated Hospital of Qingdao University and Biomedical Sciences Institute of Qingdao University (Qingdao Branch of SJTU Bio-X Institutes), Qingdao University, Qingdao, China.. Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Collaborative Innovation Center for Brain Science, Shanghai Jiao Tong University, Shanghai, China..
deCODE Genetics, Amgen, Reykjavik, Iceland..
Institute of Biological Psychiatry, Mental Health Services, Copenhagen University Hospital, Copenhagen, Denmark.. Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.. Center for GeoGenetics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.. The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Copenhagen, Denmark..
Peking University Sixth Hospital, Peking University Institute of Mental Health, Beijing, China.. National Clinical Research Center for Mental Disorders, NHC Key Laboratory of Mental Health (Peking University) and Chinese Academy of Medical Sciences Research Unit, Beijing, China..
Peking University Sixth Hospital, Peking University Institute of Mental Health, Beijing, China.. National Clinical Research Center for Mental Disorders, NHC Key Laboratory of Mental Health (Peking University) and Chinese Academy of Medical Sciences Research Unit, Beijing, China.. PKU-IDG/McGovern Institute for Brain Research, Peking University, Beijing, China..
Department of Clinical Genetics, Center for Neurogenomics and Cognitive Research, University Medical Center Amsterdam, Amsterdam, The Netherlands.. Department of Functional Genomics, Faculty of Exact Science, Center for Neurogenomics and Cognitive Research, VU University Amsterdam and VU Medical Center, Amsterdam, The Netherlands..
Department of Functional Genomics, Faculty of Exact Science, Center for Neurogenomics and Cognitive Research, VU University Amsterdam and VU Medical Center, Amsterdam, The Netherlands..
NORMENT Centre, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway.. Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway..
Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany. sripke@broadinstitute.org.. Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA. sripke@broadinstitute.org.. Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. sripke@broadinstitute.org..
MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK. WaltersJT@cardiff.ac.uk..
MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK. ODonovanMC@cardiff.ac.uk..
Issue Date: Apr-2022
Date: 2022
Publication information: Nature 2022; 604(7906): 502-508
Abstract: Schizophrenia has a heritability of 60-80%1, much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and 243,649 control individuals, we report common variant associations at 287 distinct genomic loci. Associations were concentrated in genes that are expressed in excitatory and inhibitory neurons of the central nervous system, but not in other tissues or cell types. Using fine-mapping and functional genomic data, we identify 120 genes (106 protein-coding) that are likely to underpin associations at some of these loci, including 16 genes with credible causal non-synonymous or untranslated region variation. We also implicate fundamental processes related to neuronal function, including synaptic organization, differentiation and transmission. Fine-mapped candidates were enriched for genes associated with rare disruptive coding variants in people with schizophrenia, including the glutamate receptor subunit GRIN2A and transcription factor SP4, and were also enriched for genes implicated by such variants in neurodevelopmental disorders. We identify biological processes relevant to schizophrenia pathophysiology; show convergence of common and rare variant associations in schizophrenia and neurodevelopmental disorders; and provide a resource of prioritized genes and variants to advance mechanistic studies.
URI: https://ahro.austin.org.au/austinjspui/handle/1/29989
DOI: 10.1038/s41586-022-04434-5
ORCID: 0000-0002-9565-0238
0000-0001-6548-426X
Journal: Nature
PubMed URL: 35396580
PubMed URL: https://pubmed.ncbi.nlm.nih.gov/35396580/
Type: Journal Article
Appears in Collections:Journal articles

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