Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/29932
Title: Implementing a choice of pulmonary rehabilitation models in chronic obstructive pulmonary disease (HomeBase2 trial): protocol for a cluster randomised controlled trial.
Austin Authors: Holland, Anne E ;Jones, Arwel W;Mahal, Ajay;Lannin, Natasha A;Cox, Narelle S ;Hepworth, Graham;O'Halloran, Paul;McDonald, Christine F 
Affiliation: Institute for Breathing and Sleep..
Respiratory and Sleep Medicine..
Department of Public Health, La Trobe University, Bundoora, Victoria, Australia..
Statistical Consulting Centre, The University of Melbourne, Melbourne, Victoria, Australia..
Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia..
Respiratory Research@Alfred, Central Clinical School, Monash University, Melbourne, Victoria, Australia..
Allied Health (Occupational Therapy), Alfred Health, Melbourne, Victoria, Australia..
The Nossal Global Institute for Global Health, University of Melbourne, Melbourne, Victoria, Australia..
Department of Physiotherapy, Alfred Health, Melbourne, Victoria, Australia..
Department of Clinical Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia..
Issue Date: 11-Apr-2022
Date: 2022
Publication information: BMJ open 2022; 12(4): e057311
Abstract: There is compelling evidence that either centre-based or home-based pulmonary rehabilitation improves clinical outcomes in chronic obstructive pulmonary disease (COPD). There are known health service and personal barriers which prevent potentially eligible patients from accessing the benefits of pulmonary rehabilitation. The aim of this hybrid effectiveness-implementation trial is to examine the effects of offering patients a choice of pulmonary rehabilitation locations (home or centre) compared with offering only the traditional centre-based model. This is a two-arm cluster randomised, controlled, assessor-blinded trial of 14 centre-based pulmonary rehabilitation services allocated to intervention (offering choice of home-based or centre-based pulmonary rehabilitation) or control (continuing to offer centre-based pulmonary rehabilitation only), stratified by centre-based programme setting (hospital vs non-hospital). 490 participants with COPD will be recruited. Centre-based pulmonary rehabilitation will be delivered according to best practice guidelines including supervised exercise training for 8 weeks. At intervention sites, the home-based pulmonary rehabilitation will be delivered according to an established 8-week model, comprising of one home visit, unsupervised exercise training and telephone calls that build motivation for exercise participation and facilitate self-management. The primary outcome is all-cause, unplanned hospitalisations in the 12 months following rehabilitation. Secondary outcomes include programme completion rates and measurements of 6-minute walk distance, chronic respiratory questionnaire, EQ-5D-5L, dyspnoea-12, physical activity and sedentary time at the end of rehabilitation and 12 months following rehabilitation.Direct healthcare costs, indirect costs and changes in EQ-5D-5L will be used to evaluate cost-effectiveness. A process evaluation will be undertaken to understand how the choice model is implemented and explore sustainability beyond the clinical trial. Alfred Hospital Ethics Committee has approved this protocol. The trial findings will be published in peer-reviewed journals, submitted for presentation at conferences and disseminated to patients across Australia with support from national lung charities and societies. NCT04217330.
URI: https://ahro.austin.org.au/austinjspui/handle/1/29932
DOI: 10.1136/bmjopen-2021-057311
ORCID: 0000-0003-2061-845X
0000-0003-1689-8065
0000-0002-2066-8345
0000-0002-6977-1028
0000-0001-6481-3391
Journal: BMJ open
PubMed URL: 35410931
PubMed URL: https://pubmed.ncbi.nlm.nih.gov/35410931/
Type: Journal Article
Subjects: Chronic airways disease
Emphysema
REHABILITATION MEDICINE
Appears in Collections:Journal articles

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