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Title: Opioid Prescription After Cardiac Surgery.
Austin Authors: Hui, Victor;Marhoon, Nada ;Bailey, Michael;Hua, Jackson;Yang, Bobby Ou;Seevanayagam, Siven ;Raman, Jai S ;Meyer, Ilonka;Bellomo, Rinaldo 
Affiliation: Intensive Care
Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Vic, Australia..
Department of Critical Care, The University of Melbourne, Melbourne, Vic, Australia..
Data Analytics Research and Evaluation (DARE) Centre
Cardiac Surgery
Issue Date: Apr-2022
Date: 2021
Publication information: Heart, lung & circulation 2022; 31(4): 602-609
Abstract: To characterise short-term and long-term opioid prescription patterns after cardiac surgery. We obtained data from a single Australian tertiary hospital from November 2012 to July 2019 and included 2,205 patients who underwent a primary cardiac surgical procedure. The primary outcome was the dose of opioids at hospital discharge. Secondary outcomes included factors associated with high dose opioid prescriptions and persistent opioids use after cardiac surgery. Overall, 76.4% of study patients were prescribed opioids at hospital discharge, with a median discharge prescription of 150 mg oral morphine equivalents. Moreover, 52.8% of discharge opioid prescriptions were as slow-release formulations and 60.0% of all discharge prescriptions were for patients who had received no opioids the day before discharge. In the subset of our patients with long-term data, 14.0% were still receiving opioids at 3-12 months after cardiac surgery. In cardiac surgical patients, opioid prescriptions at discharge were common, most were at higher than recommended doses and more than half were slow-release formulations. Such prescription was associated with one in seven patients continuing to receive opioids 3-12 months after surgery.
DOI: 10.1016/j.hlc.2021.08.022
ORCID: 0000-0002-7691-4779
Journal: Heart, lung & circulation
PubMed URL: 34657804
PubMed URL:
Type: Journal Article
Subjects: Anaesthesia
Cardiac surgery
Appears in Collections:Journal articles

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