Effect of a postoperative home-based exercise and self-management programme on physical function in people with lung cancer (CAPACITY): protocol for a randomised controlled trial.

Granger, Catherine L; Edbrooke, Lara; Antippa, Phillip; Wright, Gavin; McDonald, Christine F; Lamb, Karen E; Irving, Louis; Krishnasamy, Meinir; Abo, Shaza; Whish-Wilson, Georgina A; Truong, Dominic; Denehy, Linda; Parry, Selina M

doi:10.1136/bmjresp-2021-001189

Title

Effect of a postoperative home-based exercise and self-management programme on physical function in people with lung cancer (CAPACITY): protocol for a randomised controlled trial.

Publication Date

2022-01

Author(s)

Granger, Catherine L

Edbrooke, Lara

Antippa, Phillip

Wright, Gavin

McDonald, Christine F

Lamb, Karen E

Irving, Louis

Krishnasamy, Meinir

Abo, Shaza

Whish-Wilson, Georgina A

Truong, Dominic

Denehy, Linda

Parry, Selina M

Subject

exercise

lung cancer

thoracic surgery

Type of document

Journal Article

OrcId

0000-0001-6169-370X

0000-0001-6481-3391

#PLACEHOLDER_PARENT_METADATA_VALUE#

DOI

10.1136/bmjresp-2021-001189

Abstract

Exercise is important in the postoperative management of lung cancer, yet no strong evidence exists for delivery of home-based programmes. Our feasibility (phase I) study established feasibility of a home-based exercise and self-management programme (the programme) delivered postoperatively. This efficacy (phase II) study aims to determine whether the programme, compared with usual care, is effective in improving physical function (primary outcome) in patients after lung cancer surgery. This will be a prospective, multisite, two-arm parallel 1:1, randomised controlled superiority trial with assessors blinded to group allocation. 112 participants scheduled for surgery for lung cancer will be recruited and randomised to usual care (no exercise programme) or, usual care plus the 12-week programme. The primary outcome is physical function measured with the EORTC QLQ c30 questionnaire. Secondary outcomes include health-related quality of life (HRQoL); exercise capacity; muscle strength; physical activity levels and patient reported outcomes. HRQoL and patient-reported outcomes will be measured to 12 months, and survival to 5 years. In a substudy, patient experience interviews will be conducted in a subgroup of intervention participants. Ethics approval was gained from all sites. Results will be submitted for publications in peer-reviewed journals. ACTRN12617001283369.

Link

link

Citation

BMJ Open Respiratory Research 2022; 9(1): e001189

Jornal Title

BMJ Open Respiratory Research

Austin Health

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