Austin Health

Title
The Worldwide Alzheimer's Disease Neuroimaging Initiative: ADNI-3 updates and global perspectives.
Publication Date
2021-12-31
Author(s)
Weber, Christopher J
Carrillo, Maria C
Jagust, William
Jack, Clifford R
Shaw, Leslie M
Trojanowski, John Q
Saykin, Andrew J
Beckett, Laurel A
Sur, Cyrille
Rao, Naren P
Mendez, Patricio Chrem
Black, Sandra E
Li, Kuncheng
Iwatsubo, Takeshi
Chang, Chiung-Chih
Sosa, Ana Luisa
Rowe, Christopher C
Perrin, Richard J
Morris, John C
Healan, Amanda M B
Hall, Stephen E
Weiner, Michael W
Subject
Alzheimer's disease
MRI
PET
Tau
amyloid
biomarkers
cerebrospinal fluid
cognitive impairment
neuroimaging
Type of document
Journal Article
OrcId
0000-0003-3910-2453
DOI
10.1002/trc2.12226
Abstract
The Worldwide Alzheimer's Disease Neuroimaging Initiative (WW-ADNI) is a collaborative effort to investigate imaging and biofluid markers that can inform Alzheimer's disease treatment trials. It is a public-private partnership that spans North America, Argentina, Australia, Canada, China, Japan, Korea, Mexico, and Taiwan. In 2004, ADNI researchers began a naturalistic, longitudinal study that continues today around the globe. Through several successive phases (ADNI-1, ADNI-GO, ADNI-2, and ADNI-3), the study has fueled amyloid and tau phenotyping and refined neuroimaging methodologies. WW-ADNI researchers have successfully standardized analyses and openly share data without embargo, providing a rich data set for other investigators. On August 26, 2020, the Alzheimer's Association convened WW-ADNI researchers who shared updates from ADNI-3 and their vision for ADNI-4.
Link
Citation
Alzheimer's & Dementia (New York, N. Y.) 2021; 7(1): e12226
Jornal Title
Alzheimer's & Dementia (New York, N. Y.)

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