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Title: Radiotherapy planning of lymphomas: role of metabolic imaging with PET/CT.
Austin Authors: McKay, Michael J;Taubman, Kim L;Lee, Sze Ting ;Scott, Andrew M 
Affiliation: Olivia Newton-John Cancer Research Institute
Molecular Imaging and Therapy
School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia
Faculty of Medicine, University of Melbourne, Melbourne, VIC, 3052, Australia
Department of Medical Imaging, St Vincents Hospital, Fitzroy, VIC, 3065, Australia
Rural Clinical School, Northwest Regional Hospital, University of Tasmania, Burnie, TAS, 7320, Australia
Northern Cancer Service, North West Cancer Centre, Burnie, TAS, 7320, Australia
Issue Date: Feb-2022
Date: 2022-01-14
Publication information: Annals of Nuclear Medicine 2022; 36(2): 162-171
Abstract: Accurate target delineation is an absolute requirement for modern radiotherapy planning. Historically, structural imaging modalities have been used for this purpose, but there is a considerable role for functional imaging with PET/CT to contribute in this area. PET/CT's role in radiotherapy planning is well established and its use is indispensable in the clinical management of the lymphomas, particularly Hodgkin Lymphoma. A crucial use of PET/CT is as a baseline scan for delineation of the initial lymphomatous involvement, since this will determine the contouring of the gross-, clinical- and planning-target volumes (GTV, CTV, PTV). This article reviews the principles of contemporary radiotherapy, examines the evidence for the contribution of PET/CT to radiotherapy planning in lymphoma and the practicalities and challenges of applying this powerful technology to this situation.
DOI: 10.1007/s12149-021-01703-7
ORCID: 0000-0001-8641-456X
Journal: Annals of Nuclear Medicine
PubMed URL: 35028879
PubMed URL:
Type: Journal Article
Subjects: Lymphoma
Metabolic imaging
Radiotherapy planning
Appears in Collections:Journal articles

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