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Title: Role of PSMA PET/CT imaging in the diagnosis, staging and restaging of prostate cancer.
Austin Authors: Bagguley, Dominic;Ong, Sean;Buteau, James P;Koschel, Sam;Dhiantravan, Nattakorn;Hofman, Michael S;Emmett, Louise;Murphy, Declan G;Lawrentschuk, Nathan
Affiliation: Surgery (University of Melbourne)
Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, 3000, Australia
St Vincent's Hospital Nuclear Medicine & PET Department, Darlinghurst, 2010, Australia
Department of Urology, Royal Melbourne Hospital, Parkville, 3000, Australia
Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, 3000, Australia
EJ Whitten Prostate Cancer Research Centre at Epworth, Melbourne, 3121, Australia
Molecular Imaging & Therapeutic Nuclear Medicine, Peter MacCallum Cancer Centre, Melbourne, 3000, Australia
Issue Date: Jun-2021
Date: 2021-03-16
Publication information: Future Oncology 2021; 17(17): 2225-2241
Abstract: Prostate-specific membrane antigen (PSMA) PET/CT is a novel imaging technique for the detection and staging of either primary or recurrent prostate cancer. Early studies demonstrated its improved sensitivity and specificity over and in combination with other currently employed imaging techniques, such as multiparametric┬áMRI, bone scan, PET and CT. However, the lack of strength and confidence in these studies has meant incorporation of PSMA PET/CT into clinical guidelines and practice has been limited to date. In response, a number of high-quality prospective studies have recently emerged and reflect exciting results seen in preceding publications. Here we recount some of the key earlier publications, report results from the latest studies and look to the future discussing some of the eagerly awaited ongoing clinical trials.
DOI: 10.2217/fon-2020-1293
ORCID: 0000-0002-2555-9316
Journal: Future Oncology
PubMed URL: 33724868
Type: Journal Article
Subjects: PET/CT
prostate cancer
Appears in Collections:Journal articles

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