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Title: Successful Treatment of Malignant Priapism by Radiotherapy: Report of a Case, Review of the Literature, and Treatment Recommendations.
Austin Authors: Xing, Daniel T ;Yilmaz, Helene;Hettige, Supan;Hegde, Rajendra;Nair, Rohan
Affiliation: Gippsland Radiation Oncology, Latrobe Regional Hospital, Traralgon, AUS
Olivia Newton-John Cancer Wellness and Research Centre
Radiation Oncology, William Buckland Radiotherapy Centre, The Alfred Health, Melbourne, AUS
Pathology, TissuPath, Melbourne, AUS
Gippsland Radiation Oncology, Latrobe Regional Hospital, Traralgon, AUS
Issue Date: 18-Aug-2021
Date: 2021-08
Publication information: Cureus 2021; 13(8): e17287
Abstract: Malignant priapism is a condition of painful induration and erection of the penis secondary to metastatic infiltration by a neoplasm. This condition is associated with a poor prognosis. We report on a case of an 87-year-old man who presented with a painful, partially erected penis subsequent to a diagnosis of metastatic Gleason 4+5 prostate cancer. Magnetic resonance imaging (MRI) showed diffuse bilateral infiltration of his corpora cavernosa. The core biopsy of the penile nodule revealed it to be a poorly differentiated carcinoma consistent with prostatic origin. The patient's symptoms were completely resolved after treatment with high-dose palliative conformal radiotherapy (40Gy in 16 fractions). We systemically reviewed clinical reports of palliative radiotherapy for malignant priapism with the aim to gain more information on the management of this rare condition.
DOI: 10.7759/cureus.17287
Journal: Cureus
PubMed URL: 34552828
ISSN: 2168-8184
Type: Journal Article
Subjects: palliative radiation therapy
prostate cancer
volumetric modulated arc therapy
Appears in Collections:Journal articles

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