Austin Health

Title
Successful Treatment of Malignant Priapism by Radiotherapy: Report of a Case, Review of the Literature, and Treatment Recommendations.
Publication Date
2021-08-18
Author(s)
Xing, Daniel T
Yilmaz, Helene
Hettige, Supan
Hegde, Rajendra
Nair, Rohan
Subject
palliative radiation therapy
priapism
prostate cancer
radiotherapy
volumetric modulated arc therapy
Type of document
Journal Article
DOI
10.7759/cureus.17287
Abstract
Malignant priapism is a condition of painful induration and erection of the penis secondary to metastatic infiltration by a neoplasm. This condition is associated with a poor prognosis. We report on a case of an 87-year-old man who presented with a painful, partially erected penis subsequent to a diagnosis of metastatic Gleason 4+5 prostate cancer. Magnetic resonance imaging (MRI) showed diffuse bilateral infiltration of his corpora cavernosa. The core biopsy of the penile nodule revealed it to be a poorly differentiated carcinoma consistent with prostatic origin. The patient's symptoms were completely resolved after treatment with high-dose palliative conformal radiotherapy (40Gy in 16 fractions). We systemically reviewed clinical reports of palliative radiotherapy for malignant priapism with the aim to gain more information on the management of this rare condition.
Link
Citation
Cureus 2021; 13(8): e17287
Jornal Title
Cureus
ISSN
2168-8184

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