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https://ahro.austin.org.au/austinjspui/handle/1/27418| Title: | What Is T+? A Gordian Knot of Tracers, Thresholds, and Topographies. | Austin Authors: | Villemagne, Victor L ;Lopresti, Brian J;Doré, Vincent ;Tudorascu, Dana;Ikonomovic, Milos D;Burnham, Samantha;Minhas, Davneet;Pascoal, Tharick A;Mason, N Scott;Snitz, Beth;Aizenstein, Howard;Mathis, Chester A;Lopez, Oscar;Rowe, Christopher C ;Klunk, William E;Cohen, Ann D | Affiliation: | Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania Center for Alzheimer Research and Treatment, Brigham and Women's Hospital and Massachusetts General Hospital, Boston, Massachusetts CSIRO Health and Biosecurity, Melbourne, Victoria, Australia Molecular Imaging and Therapy School of Medical and Health Sciences, Edith Cowan University, Perth, Washington, Australia Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania |
Issue Date: | 10-May-2021 | Date: | 2020-12-31 | Publication information: | Journal of Nuclear Medicine 2021; 62(5): 614-619 | Abstract: | In this review we examine, in the context of the amyloid, tau, and neurodegeneration framework, the available evidence and potential alternatives on how to establish tau positivity (T+) for multiple tau-imaging tracers in order to reach a consensus on normal and abnormal tau imaging values that can be universally implemented in clinical research and therapeutic trials. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/27418 | DOI: | 10.2967/jnumed.120.245423 | Journal: | Journal of Nuclear Medicine | PubMed URL: | 33384320 | Type: | Journal Article | Subjects: | AT(N) framework Alzheimer disease biomarkers brain imaging tau imaging |
| Appears in Collections: | Journal articles |
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