Austin Health

Title
OnabotulinumtoxinA in Migraine: A Review of the Literature and Factors Associated with Efficacy.
Publication Date
2021-06-29
Author(s)
Ray, Jason C
Hutton, Elspeth J
Matharu, Manjit
Subject
botulinum toxin
migraine
predictors of efficacy
Type of document
Journal Article
OrcId
0000-0003-4833-5507
0000-0002-8543-7767
0000-0002-4960-2294
DOI
10.3390/jcm10132898
Abstract
The efficacy of onabotulinumtoxinA (OnaB-A) as a preventative treatment for chronic migraine, emerging fortuitously from clinical observation is now supported by class one evidence and over two decades of real-world clinical data. There is still limited ability to predict a clinically meaningful response to OnaB-A for individual patients, however. This review summarises briefly the proposed mechanism of OnaB-A in chronic migraine, the literature of predictors of clinical response, and recent developments in the field.
Link
Citation
Journal of Clinical Medicine 2021; 10(13): 2898
Jornal Title
Journal of Clinical Medicine
ISSN
2077-0383

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