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Title: Matched Case-Control Study of the Long-Term Impact of Beta-Lactam Antibiotic Allergy Testing.
Austin Authors: Trubiano, Jason ;Marhoon, Nada ;Vogrin, Sara;Chua, Kyra Y L ;Holmes, Natasha E 
Affiliation: Centre for Antibiotic Allergy and Research
Centre for Integrated Critical Care, University of Melbourne, Melbourne, Australia
The National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Australia
Medicine (University of Melbourne)
Data Analytics Research and Evaluation (DARE) Centre
Department of Medicine (St. Vincent's Hospital), University of Melbourne, Melbourne, Australia
Infectious Diseases
Issue Date: 17-Nov-2020
Date: 2020-11-17
Publication information: Antimicrobial Agents and Chemotherapy 2020; 64(12): e01823-20
Abstract: Whereas the short-term impacts of antibiotic allergy testing on delabeling and antibiotic usage have been demonstrated, the long-term impacts have been less well defined. In a single-center matched case-control study from Melbourne, Australia, we demonstrate that a beta-lactam antibiotic allergy testing program has a significant impact on antibiotic usage and infection-related outcomes. This study supports implementation of an antibiotic allergy testing program as a standard of care of antimicrobial stewardship programs.
DOI: 10.1128/AAC.01823-20
ORCID: 0000-0002-5111-6367
Journal: Antimicrobial Agents and Chemotherapy
PubMed URL: 32988819
Type: Journal Article
Subjects: adverse drug effects
allergy testing
antibiotic allergy
antimicrobial allergy
antimicrobial resistance
antimicrobial stewardship
beta-lactam allergy
penicillin allergy
Appears in Collections:Journal articles

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