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Title: | Treatment of Community-Acquired Pneumonia in Immunocompromised Adults: A Consensus Statement Regarding Initial Strategies. | Austin Authors: | Ramirez, Julio A;Musher, Daniel M;Evans, Scott E;Dela Cruz, Charles;Crothers, Kristina A;Hage, Chadi A;Aliberti, Stefano;Anzueto, Antonio;Arancibia, Francisco;Arnold, Forest;Azoulay, Elie;Blasi, Francesco;Bordon, Jose;Burdette, Steven;Cao, Bin;Cavallazzi, Rodrigo;Chalmers, James;Charles, Patrick G P ;Chastre, Jean;Claessens, Yann-Erick;Dean, Nathan;Duval, Xavier;Fartoukh, Muriel;Feldman, Charles;File, Thomas;Froes, Filipe;Furmanek, Stephen;Gnoni, Martin;Lopardo, Gustavo;Luna, Carlos;Maruyama, Takaya;Menendez, Rosario;Metersky, Mark;Mildvan, Donna;Mortensen, Eric;Niederman, Michael S;Pletz, Mathias;Rello, Jordi;Restrepo, Marcos I;Shindo, Yuichiro;Torres, Antoni;Waterer, Grant;Webb, Brandon;Welte, Tobias;Witzenrath, Martin;Wunderink, Richard | Affiliation: | Department of Pathophysiology and Transplantation, University of Milan, and Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Respiratory Unit and Cystic Fibrosis Adult Center, Milan, Italy Division of Infectious Diseases, University of Louisville, Louisville, KY Department of Medicine, University of Melbourne, Australia School of Medicine, University of Western Australia, Perth, Australia Baylor College of Medicine and Michael E. DeBakey VA Medical Center, Houston, TX Department of Pulmonary Medicine, University of Texas MD Anderson Cancer Center, Houston, TX Pulmonary, Critical Care and Sleep Medicine, Yale University, New Haven, CT Veterans Puget Sound Health Care System, University of Washington, Seattle WA Thoracic Transplant Program, Indiana University, Indianapolis, IN South Texas Veterans Health Care System, Audie L. Murphy Memorial Veterans Hospital, and University of Texas Health, San Antonio, TX Pneumology Service, Instituto Nacional del Tórax and Clínica Santa María, Santiago de Chile, Chile Division of Infectious Diseases, University of Louisville, Louisville, KY Medical ICU, Saint-Louis Teaching Hospital, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France Section of Infectious Diseases, Providence Health Center, Washington, DC Wright State University Boonshoft School of Medicine, Dayton, OH Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, China-Japan Friendship Hospital, Beijing, China Division of Pulmonary, Critical Care, and Sleep Disorders Medicine, University of Louisville, Louisville, KY Scottish Centre for Respiratory Research, School of Medicine, Ninewells Hospital and Medical School, Dundee, UK Service de Médecine Intensive-Réanimation, Hôpital La Pitié-Salpêtrière, Sorbonne Université, APHP, Paris, France Department of Emergency Medicine, Centre Hospitalier Princesse Grace, Monaco. Intermountain Medical Center and the University of Utah, Salt Lake City, UT UMR 1137, IAME, INSERM, and CIC 1425, Hôpital Bichat-Claude Bernard, APHP, Paris, France Service de Médecine Intensive Réanimation, Hôpital Tenon, APHP, and APHP, Sorbonne Université, Faculté de Médecine Sorbonne Université, Paris, France Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa Infectious Disease Section, Northeast Ohio Medical University and Infectious Disease Division, Summa Health, Akron, OH ICU, Chest Department, Hospital Pulido Valente-Centro Hospitalar Universitário Lisboa Norte, Lisbon, Portugal Division of Infectious Diseases, University of Louisville, Louisville, KY Fundación del Centro de Estudios Infectológicos, Buenos Aires, Argentina Pulmonary Diseases Division, Universidad de Buenos Aires, Buenos Aires, Argentina Department of Respiratory Medicine, National Hospital Organization Mie National Hospital, Tsu, Japan Pneumology Department, La Fe University and Polytechnic Hospital, La Fe Health Research Institute, Valencia, Spain Division of Pulmonary, Critical Care and Sleep Medicine and Center for Bronchiectasis Care, University of Connecticut Health, Farmington, CT Icahn School of Medicine at Mount Sinai, New York, NY Department of Medicine, University of Connecticut Health Center, Farmington, CT Pulmonary and Critical Care, New York Presbyterian/Weill Cornell Medical Center and Weill Cornell Medical College, New York, NY Institute for Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany Centro de Investigacion Biomedica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, and Infections Area, Vall d'Hebron Institute of Research, Barcelona, Spain South Texas Veterans Health Care System, Audie L. Murphy Memorial Veterans Hospital, and University of Texas Health, San Antonio, TX Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan Servei de Pneumologia, Hospital Clinic, Universitat de Barcelona. Barcelona, CIBERES, Spain Division of Infectious Diseases and Clinical Epidemiology, Intermountain Healthcare, Salt Lake City, UT and Division of Infectious Diseases and Geographic Medicine, Stanford Medicine, Palo Alto, CA German Center for Lung Research, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH) Clinic of Pneumology, Hannover Medical School, Hannover, Germany Division of Pulmonary Inflammation and Department of Infectious Diseases and Respiratory Medicine, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, Chicago, IL Infectious Diseases |
Issue Date: | Nov-2020 | Date: | 2020-01-16 | Publication information: | Chest 2020; 158(5): 1896-1911 | Abstract: | Community-acquired pneumonia (CAP) guidelines have improved the treatment and outcomes of patients with CAP, primarily by standardization of initial empirical therapy. But current society-published guidelines exclude immunocompromised patients. There is no consensus regarding the initial treatment of immunocompromised patients with suspected CAP. This consensus document was created by a multidisciplinary panel of 45 physicians with experience in the treatment of CAP in immunocompromised patients. The Delphi survey methodology was used to reach consensus. The panel focused on 21 questions addressing initial management strategies. The panel achieved consensus in defining the population, site of care, likely pathogens, microbiologic workup, general principles of empirical therapy, and empirical therapy for specific pathogens. This document offers general suggestions for the initial treatment of the immunocompromised patient who arrives at the hospital with pneumonia. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/26663 | DOI: | 10.1016/j.chest.2020.05.598 | Journal: | Chest | PubMed URL: | 32561442 | Type: | Journal Article | Subjects: | community-acquired pneumonia immunocompromised pneumonia |
Appears in Collections: | Journal articles |
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