Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/26460
Title: Bortezomib for treatment-refractory autoimmune haemolytic anaemia following multivisceral transplantation.
Austin Authors: Wong, Darren;Thomas, William;Butler, Andrew;Sharkey, Lisa
Affiliation: Gastroenterology and Hepatology
Department of Gastroenterology, Addenbrooke's Hospital, Cambridge, UK
Department of Surgery, Addenbrooke's Hospital, Cambridge, UK
Department of Haematology, Addenbrooke's Hospital, Cambridge, UK
Issue Date: 12-May-2021
Date: 2021
Publication information: BMJ Case Reports 2021; 14(5):e241634
Abstract: A 25-year-old man who received alemtuzumab as induction therapy for a multivisceral transplant experienced delayed onset of warm autoimmune haemolytic anaemia and neutropaenia. Serological testing and bone marrow biopsy excluded alternative causes. Haemolysis was refractory to standard therapies including corticosteroids, intravenous immunoglobulin and rituximab. The patient was successfully treated with bortezomib, a proteasome inhibitor, and has remained well as an outpatient without evidence of ongoing haemolysis.
URI: https://ahro.austin.org.au/austinjspui/handle/1/26460
DOI: 10.1136/bcr-2021-241634
ORCID: 0000-0003-1490-0547
Journal: BMJ Case Reports
PubMed URL: 33980556
Type: Journal Article
Subjects: GI bleeding
haematology (drugs and medicines)
transplantation
Appears in Collections:Journal articles

Show full item record

Page view(s)

46
checked on Dec 21, 2024

Google ScholarTM

Check


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.