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Title: Biomarkers for Cancer Cachexia: A Mini Review.
Austin Authors: Cao, Zhipeng;Zhao, Kening;Jose, Irvin;Hoogenraad, Nick J;Osellame, Laura D
Affiliation: Department of Biochemistry and Genetics, La Trobe University, Bundoora, VIC 3086, Australia
Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
Olivia Newton-John Cancer Research Institute
Issue Date: 26-Apr-2021
Date: 2021-04-26
Publication information: International Journal of Molecular Sciences 2021; 22(9): 4501
Abstract: Cancer cachexia is a common condition in many cancer patients, particularly those with advanced disease. Cancer cachexia patients are generally less tolerant to chemotherapies and radiotherapies, largely limiting their treatment options. While the search for treatments of this condition are ongoing, standards for the efficacy of treatments have yet to be developed. Current diagnostic criteria for cancer cachexia are primarily based on loss of body mass and muscle function. However, these criteria are rather limiting, and in time, when weight loss is noticeable, it may be too late for treatment. Consequently, biomarkers for cancer cachexia would be valuable adjuncts to current diagnostic criteria, and for assessing potential treatments. Using high throughput methods such as "omics approaches", a plethora of potential biomarkers have been identified. This article reviews and summarizes current studies of biomarkers for cancer cachexia.
DOI: 10.3390/ijms22094501
ORCID: 0000-0003-4142-6190
Journal: International Journal of Molecular Sciences
PubMed URL: 33925872
Type: Journal Article
Subjects: biomarkers
cachexia-inducing factors
cancer cachexia
Appears in Collections:Journal articles

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