Austin Health

Title
Impact of inflammatory bowel disease and azathioprine on long-term outcomes after liver transplantation for primary sclerosing cholangitis.
Publication Date
2021-05
Author(s)
Peverelle, Matthew R
De Cruz, Peter P
Paleri, Sarang
Gow, Paul J
Subject
Mortality
Recurrent primary sclerosing cholangitis
Type of document
Journal Article
DOI
10.1002/lt.26009
Abstract
We read with interest the multicentre retrospective study by Irlès-Depé et al1 reporting the impact of inflammatory bowel disease (IBD) on long-term outcomes after liver transplantation (LT) for primary sclerosing cholangitis (PSC). In their series PSC-IBD patients were found to have similar rates of death, recurrent PSC (rPSC) and malignancy as patients with isolated PSC. Moreover azathioprine (AZA) exposure was associated with increased mortality, an association which may have been due to an era effect.
Link
Citation
Liver Transplantation 2021; 27(5): 770-771
Jornal Title
Liver Transplantation

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