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Title: A Retrospective Study of Ultrasound Accuracy for the Diagnosis of Chronic Inflammatory Demyelinating Polyneuropathy.
Austin Authors: Crump, Nicholas H ;Cartwright, Michael S
Affiliation: Neurology
Department of Neurology, Wake Forest School of Medicine, Winston-Salem, North Carolina, U.S.A
Medicine (University of Melbourne)
Issue Date: 2022 2020-09-28
Publication information: Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society 2022-05-01; 39(4): 312-316
Abstract: Ultrasound is emerging as a useful tool for the evaluation of immune-mediated neuropathies because it can provide high-resolution anatomic information to complement electrodiagnostic data. Nerve enlargements are commonly found in chronic inflammatory demyelinating polyneuropathy (CIDP), and their presence likely useful in diagnosis, particularly if multifocal. In this study, the authors undertook a retrospective chart review to identify ultrasound findings in patients with CIDP previously studied in a single busy neurodiagnostic laboratory. Of the 50 cases identified from 2000 to 2017, individuals with a confirmed diagnosis of CIDP (21 cases) were more likely to have multiple sites of enlargement, as well as more pronounced nerve enlargement, than patients who were subsequently found to have an alternate cause of neuropathy (22 cases). The presence of any moderately enlarged nerve segment predicted definite CIDP with sensitivity of 81% and specificity 77%. This study demonstrates that ultrasound can be of diagnostic utility in patients with suspected CIDP, even when conducted in a nonstandardized real-world setting.
DOI: 10.1097/WNP.0000000000000782
Journal: Journal of Clinical Neurophysiology
PubMed URL: 33009042
Type: Journal Article
Appears in Collections:Journal articles

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