Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/23833
Title: Prevalence, Characteristics, Risk Factors, and Outcomes of Invasively Ventilated COVID-19 Patients with Acute Kidney Injury and Renal Replacement Therapy.
Austin Authors: Fominskiy, Evgeny V;Scandroglio, Anna Mara;Monti, Giacomo;CalabrĂ², Maria Grazia;Landoni, Giovanni;Dell'Acqua, Antonio;Beretta, Luigi;Moizo, Elena;Ravizza, Alfredo;Monaco, Fabrizio;Campochiaro, Corrado;Pieri, Marina;Azzolini, Maria Luisa;Borghi, Giovanni;Crivellari, Martina;Conte, Caterina;Mattioli, Cristina;Silvani, Paolo;Mucci, Milena;Turi, Stefano;Tentori, Stefano;Baiardo Redaelli, Martina;Sartorelli, Marianna;Angelillo, Piera;Belletti, Alessandro;Nardelli, Pasquale;Nisi, Francesco Giuseppe;Valsecchi, Gabriele;Barberio, Cristina;Ciceri, Fabio;Serpa Neto, Ary ;Dagna, Lorenzo;Bellomo, Rinaldo ;Zangrillo, Alberto
Affiliation: Department of Critical Care Medicine, Hospital Israelita Albert Einstein, Sao Paulo, Brazil
Department of Hematology and Stem Cell Transplantation, IRCCS San Raffaele Scientific Institute, Milan, Italy
Transplant Medicine, IRCCS San Raffaele Scientific Institute, Milan, Italy
Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia
Department of Intensive Care, Austin Health, Heidelberg, Victoria, Australia
Department of Intensive Care, Royal Melbourne Hospital, Melbourne, Victoria, Australia
Centre for Integrated Critical Care, School of Medicine, The University of Melbourne, Melbourne, Victoria, Australia
Data Analytics Research and Evaluation (DARE) Centre, Austin Health and The University of Melbourne, Heidelberg, Victoria, Australia
Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy
Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy
Faculty of Medicine, Vita-Salute San Raffaele University, Milan, Italy
Department of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy
Issue Date: 13-Jul-2020
Date: 2020-07-13
Publication information: Blood Purification 2020; online first: 13 July
Abstract: There is no information on acute kidney injury (AKI) and continuous renal replacement therapy (CRRT) among invasively ventilated coronavirus disease 2019 (COVID-19) patients in Western healthcare systems. To study the prevalence, characteristics, risk factors and outcome of AKI and CRRT among invasively ventilated COVID-19 patients. Observational study in a tertiary care hospital in Milan, Italy. Among 99 patients, 72 (75.0%) developed AKI and 17 (17.7%) received CRRT. Most of the patients developed stage 1 AKI (33 [45.8%]), while 15 (20.8%) developed stage 2 AKI and 24 (33.4%) a stage 3 AKI. Patients who developed AKI or needed CRRT at latest follow-up were older, and among CRRT treated patients a greater proportion had preexisting CKD. Hospital mortality was 38.9% for AKI and 52.9% for CRRT patients. Among invasively ventilated COVID-19 patients, AKI is very common and CRRT use is common. Both carry a high risk of in-hospital mortality.
URI: https://ahro.austin.org.au/austinjspui/handle/1/23833
DOI: 10.1159/000508657
ORCID: 0000-0002-1650-8939
Journal: Blood Purification
PubMed URL: 32659757
Type: Journal Article
Subjects: Acute kidney injury
Coronavirus
Coronavirus disease 2019
Critical care
Renal replacement therapy
COVID-19
Appears in Collections:Journal articles

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