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Title: "Management of Community-Acquired Pneumonia in Immunocompromised Adults: A Consensus Statement Regarding Initial Strategies".
Austin Authors: Ramirez, Julio A;Musher, Daniel M;Evans, Scott E;Dela Cruz, Charles;Crothers, Kristina A;Hage, Chadi A;Aliberti, Stefano;Anzueto, Antonio;Arancibia, Francisco;Arnold, Forest;Azoulay, Elie;Blasi, Francesco;Bordon, Jose;Burdette, Steven;Cao, Bin;Cavallazzi, Rodrigo;Chalmers, James;Charles, Patrick G P ;Chastre, Jean;Claessens, Yann-Erick;Dean, Nathan;Duval, Xavier;Fartoukh, Muriel;Feldman, Charles;File, Thomas;Froes, Filipe;Furmanek, Stephen;Gnoni, Martin;Lopardo, Gustavo;Luna, Carlos;Maruyama, Takaya;Menendez, Rosario;Metersky, Mark;Mildvan, Donna;Mortensen, Eric;Niederman, Michael S;Pletz, Mathias;Rello, Jordi;Restrepo, Marcos I;Shindo, Yuichiro;Torres, Antoni;Waterer, Grant;Webb, Brandon;Welte, Tobias;Witzenrath, Martin;Wunderink, Richard
Affiliation: Division of Infectious Diseases, University of Louisville, Louisville, KY, USA
Department of Infectious Diseases, Austin Health, Heidelberg, Victoria, Australia
Department of Medicine, University of Melbourne, Australia
Division of Infectious Diseases and Geographic Medicine, Stanford Medicine, Palo Alto, CA, USA
Division of Infectious Diseases and Clinical Epidemiology, Intermountain Healthcare, Salt Lake City, UT
Providence Health Center, Section of Infectious Diseases, Washington, DC, USA
Baylor College of Medicine and Michael E. DeBakey VA Medical Center, Houston, TX, USA
Department of Pulmonary Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA
Pulmonary, Critical Care and Sleep Medicine, Yale University, New Haven, CT, USA
Veterans Puget Sound Health Care System, University of Washington, Seattle WA, USA
Thoracic Transplant Program, Indiana University, Indianapolis, IN, USA
South Texas Veterans Health Care System Audie L. Murphy and University of Texas Health San Antonio, TX, USA
Division of Infectious Diseases, University of Louisville, Louisville, KY, USA
Wright State University Boonshoft School of Medicine, Dayton, OH, USA
Division of Pulmonary, Critical Care, and Sleep Disorders Medicine, University of Louisville, Louisville, KY, USA
Intermountain Medical Center and the University of Utah, Salt Lake City, Utah, USA
Infectious Disease Section, Northeast Ohio Medical University and Infectious Disease Division, Summa Health, Akron, OH, USA
Division of Pulmonary, Critical Care and Sleep Medicine and Center for Bronchiectasis Care, University of Connecticut Health, Farmington, CT, USA
Icahn School of Medicine at Mount Sinai, New York, NY,USA
Department of Medcine, University of Connecticut Health Center, Farmington, CT, USA
Pulmonary and Critical Care New York Presbyterian/ Weill Cornell Medical Center and Weill Cornell Medical College, New York, NY, USA
Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Department of Pathophysiology and Transplantation, University of Milan, and Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Respiratory Unit and Cystic Fibrosis Adult Center, Milan, Italy
Scottish Centre for Respiratory Research, School of Medicine, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK
School of Medicine, University of Western Australia, Perth, Australia
Pneumology Service, Instituto Nacional del Tórax and Clínica Santa María, Santiago de Chile, Chile
Medical Intensive Care Unit, Saint-Louis Teaching Hospital, APHP, Paris, France
Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, China-Japan Friendship Hospital, Beijing, China
Service de Médecine Intensive - Réanimation, Hôpital La Pitié-Salpêtrière, Sorbonne Université,Assistance Publique-Hôpitaux de Paris, Paris, France
Department of emergency medicine, Centre Hospitalier Princesse Grace, avenue Pasteur 98012 Monaco
UMR 1137, IAME, INSERM, and CIC 1425, Hôpital Bichat-Claude Bernard, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France
Service de Médecine intensive Réanimation, Hôpital Tenon, Assistance Publique Hôpitaux de Paris, and AP-HP.Sorbonne Université, Faculté de Médecine Sorbonne Université, Paris, France
Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Intensive Care Unit, Chest Department, Hospital Pulido Valente - Centro Hospitalar Universitário Lisboa Norte, Lisbon, Portugal
Fundación del Centro de Estudios Infectológicos, Buenos Aires, Argentina
Pulmonary Diseases Division, Universidad de Buenos Aires, Buenos Aires, Argentina
Department of Respiratory Medicine, National Hospital Organization Mie National Hospital, Tsu, Japan
Pneumology Department, La Fe University and Polytechnic Hospital, La Fe Health Research Institute, 46026 Valencia, Spain
Institute for Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany
Centro de Investigacion Biomedica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, and Infections Area, Vall d'Hebron Institute of research (VHIR), Barcelona, Spain
Department of Respiratory Medicine,Nagoya University Graduate School of Medicine 65 Tsurumai-cho, Showa-ku, Nagoya, Japan
Servei de Pneumologia. Hospital Clinic. Universitat de Barcelona. Barcelona . CIBERES . Spain
German Center for Lung Research (DZL), Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH) Clinic of Pneumology, Hannover Medical School, Hannover, Germany
Division of Pulmonary Inflammation and Department of Infectious Diseases and Respiratory Medicine, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, German
Issue Date: 16-Jun-2020 2020-06-16
Publication information: Chest 2020; online first: 16 June
Abstract: Community-acquired pneumonia (CAP) guidelines have improved the management and outcomes of patients with CAP, primarily by standardization of initial empiric therapy. But current society-published guidelines exclude immunocompromised patients. There is no concensus regarding the initial management of immunocompromised patients with suspected CAP. This consensus document was created by a multidisciplinary panel of 45 physicians with experience in the management of CAP in immunocompromised patients. The Delphi survey methodology was used to reach consensus. The panel focused on 21 questions addressing initial management strategies. The panel achieved consensus in defining the population, site of care, likely pathogens, microbiological work-up, general principles of empiric therapy, and empiric therapy for specific pathogens. This document offer general suggestions for the initial management of the immunocompromised patient who arrives at the hospital with pneumonia.
DOI: 10.1016/j.chest.2020.05.598
PubMed URL: 32561442
Type: Journal Article
Appears in Collections:Journal articles

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