Austin Health

Title
Ischaemic heart disease and Cancer: competing malignant conditions.
Publication Date
2020-05-27
Author(s)
Murphy, Alexandra C
Koshy, Anoop N
Yudi, Matias B
Type of document
Journal Article
OrcId
0000-0002-3706-4150
0000-0002-4248-7537
0000-0002-8741-8631
DOI
10.1186/s12872-020-01539-5
Abstract
The growing population of cancer survivors and their high frequency of cardiovascular disease have resulted in a dramatic increase in cancer patients requiring cardiovascular intervention. However, there is a lack of evidence to guide optimal management in this complex population who have historically been excluded from cardiovascular trials. We review the recently published meta-analysis by Roule et al. The findings of this analysis demonstrate that patients with cancer presenting with acute coronary syndrome (ACS) have increased rates of in-hospital cardiovascular mortality, bleeding and one-year cardiovascular mortality. All-cause mortality measured in-hospital and at one-year were also significantly greater in cancer patients as was all-cause mortality in cancer patients that undergo percutaneous coronary intervention (PCI). In contrast to the short-term outcomes, rates of long-term cardiovascular mortality did not differ significantly between groups. Patient-specific assessment of risk, accounting for disease characteristics and treatment, and close communication with oncology providers is vital in defining optimal treatment strategies in this population.
Link
Citation
BMC Cardiovascular Disorders 2020; 20(1): 254
Jornal Title
BMC Cardiovascular Disorders

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