Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/22914
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dc.contributor.authorSeah, Jas-Mine-
dc.contributor.authorKam, Ning Mao-
dc.contributor.authorWong, Lydia-
dc.contributor.authorTanner, Cara-
dc.contributor.authorShub, Alexis-
dc.contributor.authorEkinci, Elif I-
dc.contributor.authorHoulihan, Christine-
dc.date2020-04-01-
dc.date.accessioned2020-04-14T04:00:52Z-
dc.date.available2020-04-14T04:00:52Z-
dc.date.issued2020-04-01-
dc.identifier.citationInternal Medicine Journal 2020; online first: 1 April-
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/22914-
dc.description.abstractOur aim was to explore differences in pregnancy outcomes between women with type 1 and type 2 diabetes, and healthy controls, and to examine the relationships between potential adverse risk factors and pregnancy outcomes in this cohort of women. This is a 10 year retrospective study of women with type 1 diabetes (n = 92), type 2 diabetes (n = 106) and healthy women without diabetes (controls) (n = 119) from a tertiary obstetric centre. Clinical and biochemical characteristics of women with type 1 and type 2 diabetes were determined and related to major obstetric outcomes using univariate analysis. Women with pre-existing diabetes had higher adverse pregnancy outcomes (preeclampsia, emergency caesarean section, preterm birth <32 and 37 weeks, large for gestational age, neonatal jaundice, Apgar score < 7 at 5 min, neonatal intensive care admission and neonatal hypoglycaemia) compared to controls. A higher birth weight gestational centile (97.4% vs. 72.4%, P = 0.001) and large for gestational age rate (63.4% vs. 35.8%, P = 0.001) were observed in type 1 diabetes compared to type 2 diabetes. There were no differences in other outcomes between women with type 1 and 2 diabetes. In this exploratory study, risk factors for maternal adverse outcomes differ between type 1 and type 2 diabetes. Maternal and fetal adverse outcomes were higher in pregnancies affected by diabetes compared to healthy women but occurred with similar frequency in women with type 1 and type 2 diabetes. This article is protected by copyright. All rights reserved.-
dc.language.isoeng-
dc.titleRisk factors for pregnancy outcomes in type 1 and type 2 diabetes.-
dc.typeJournal Article-
dc.identifier.journaltitleInternal Medicine Journal-
dc.identifier.affiliationDepartment of Medicine Austin Health, The University of Melbourne, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationDepartment of Perinatal Medicine Mercy Health, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationDepartment of Endocrinology Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.doi10.1111/imj.14840-
dc.identifier.orcid0000-0001-5528-3966-
dc.identifier.orcid0000-0003-2372-395X-
dc.identifier.pubmedid32237194-
dc.type.austinJournal Article-
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