Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/22833
Title: SJS/TEN 2019: From science to translation.
Austin Authors: Chang, Wan-Chun;Abe, Riichiro;Anderson, Paul;Anderson, Wanpen;Ardern-Jones, Michael R;Beachkofsky, Thomas M;Bellón, Teresa;Biala, Agnieszka K;Bouchard, Charles;Cavalleri, Gianpiero L;Chapman, Nicole;Chodosh, James;Choi, Hyon K;Cibotti, Ricardo R;Divito, Sherrie J;Dewar, Karen;Dehaeck, Ulrike;Etminan, Mahyar;Forbes, Diane;Fuchs, Esther;Goldman, Jennifer L;Holmes, James H;Hope, Elyse A;Hung, Shuen-Iu;Hsieh, Chia-Ling;Iovieno, Alfonso;Jagdeo, Julienne;Kim, Mee Kum;Koelle, David M;Lacouture, Mario E;Le Pallec, Sophie;Lehloenya, Rannakoe J;Lim, Robyn;Lowe, Angie;McCawley, Jean;McCawley, Julie;Micheletti, Robert G;Mockenhaupt, Maja;Niemeyer, Katie;Norcross, Michael A;Oboh, Douglas;Olteanu, Cristina;Pasieka, Helena B;Peter, Jonathan;Pirmohamed, Munir;Rieder, Michael;Saeed, Hajirah N;Shear, Neil H;Shieh, Christine;Straus, Sabine;Sukasem, Chonlaphat;Sung, Cynthia;Trubiano, Jason A ;Tsou, Sheng-Ying;Ueta, Mayumi;Volpi, Simona;Wan, Chen;Wang, Hongsheng;Wang, Zhao-Qing;Weintraub, Jessica;Whale, Cindy;Wheatley, Lisa M;Whyte-Croasdaile, Sonia;Williams, Kristina B;Wright, Galen;Yeung, Sonia N;Zhou, Li;Chung, Wen-Hung;Phillips, Elizabeth J;Carleton, Bruce C
Affiliation: Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada; British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada
Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA
Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Association des malades des syndromes de Lyell et de Stevens-Johnson (Amalyste), Paris, France
Institute of Dermatology, Chinese Academy of Medical Sciences, National Center for STD and Leprosy Control, China CDC, Nanjing, China
Wilford Hall Ambulatory Surgical Center, Lackland Air Force Base, TX, USA
SJS Awareness Oregon, Klamath Falls, OR, USA
Stevens-Johnson Syndrome Foundation, Westminster, CO, USA
SJ Syndrome of Texas, Austin, TX, USA
Division of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA
National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA
Division of Pharmacovigilance I, Office of Surveillance and Epidemiology, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, USA
National Human Genome Research Institute, NIH, Bethesda, MD, USA
Department of Ophthalmology, Vanderbilt Eye Institute, Nashville, TN, USA
Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA
Department of Dermatology, MedStar Washington Hospital Center, Washington, DC, USA
Laboratory of Immunology, Division of Biotechnology Review and Research III (DBRR III), Office of Biotechnology Products (OBP), Office of Pharmaceutical Quality (OPQ), Center for Drug Evaluation and Research (CDER), FDA, Silver Spring, MD, USA
Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Memorial Sloan Kettering Cancer Center, New York, NY, USA
Department of Medicine, University of Washington, Seattle, WA, USA
Wake Forest University School of Medicine, WFBMC Burn Center, Winston-Salem, NC, USA
Children's Mercy Hospital Kansas City, Kansas City, MO, USA
Department of Obstetrics and Gynecology, University of Washington, Seattle, WA, USA
Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD, USA
Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA, USA
Loyola University Medical Center, Chicago, IL, USA
Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Australia
Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
Department of Infectious Diseases, Austin Health, Heidelberg, Victoria, Australia
Department of Ophthalmology, Seoul National University College of Medicine, Seoul, South Korea
School of Pharmacy and Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland; FutureNeuro SFI Research Centre, Royal College of Surgeons in Ireland, Dublin, Ireland
Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK
Drug Hypersensitivity Group, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain
Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada; British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada
Genome Canada, Ottawa, ON, Canada
Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada
Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada
Canadian Institutes of Health Research, Ottawa, ON, Canada
Genome British Columbia, Vancouver, BC, Canada
Cancer Vaccine and Immune Cell Therapy Core Laboratory, Chang Gung Immunology Consortium, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan; Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan
Eden Social Welfare Foundation, Taipei, Taiwan
Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver General Hospital Eye Care Center, Vancouver, BC, Canada
Genome British Columbia, Vancouver, BC, Canada
Division of Dermatology, Department of Medicine, University of Cape Town, Cape Town, South Africa
Health Products and Food Branch, Health Canada, Ottawa, ON, Canada
SJS/TEN International Awareness (STIA), Lucky Lake, SK, Canada
Dokumentationszentrum schwerer Hautreaktionen (dZh), Department of Dermatology, Medical Center and Medical Faculty, University of Freiburg, Freiburg, Germany
Division of Dermatology, Department of Medicine, University of Alberta, Edmonton, AB, Canada
Division of Allergy and Clinical Immunology, Department of Medicine, University of Cape Town, Cape Town, South Africa
Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK
Department of Paediatrics, Children's Hospital/London Health Sciences Centre, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada
Sunnybrook Health Sciences Centre, University of Toronto, ON, Canada
Dutch Medicines Evaluation Board, Pharmacovigilance Risk Assessment Committee, European Medicines Agency, Utrecht, the Netherlands
Health Products Regulation Group, Health Sciences Authority Singapore, Duke-NUS Medical School, Singapore
Eden Social Welfare Foundation, Taipei, Taiwan
Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
Genome British Columbia, Vancouver, BC, Canada
Eden Social Welfare Foundation, Taipei, Taiwan
SJS Canada, Brantford, ON, Canada
Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada; British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada
Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver General Hospital Eye Care Center, Vancouver, BC, Canada
Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou, Taipei, Keelung, Taoyuan, Taiwan; Cancer Vaccine and Immune Cell Therapy Core Laboratory, Chang Gung Immunology Consortium, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan; Department of Dermatology, Xiamen Chang Gung Hospital, Xiamen, China; Whole-Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital, Keelung, Taiwan.
Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada; British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.
Issue Date: Apr-2020
metadata.dc.date: 2020-03-07
Publication information: Journal of Dermatological Science 2020; 98(1): 2-12
Abstract: Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are potentially life-threatening, immune-mediated adverse reactions characterized by widespread erythema, epidermal necrosis, and detachment of skin and mucosa. Efforts to grow and develop functional international collaborations and a multidisciplinary interactive network focusing on SJS/TEN as an uncommon but high burden disease will be necessary to improve efforts in prevention, early diagnosis and improved acute and long-term management. SJS/TEN 2019: From Science to Translation was a 1.5-day scientific program held April 26-27, 2019, in Vancouver, Canada. The meeting successfully engaged clinicians, researchers, and patients and conducted many productive discussions on research and patient care needs.
URI: http://ahro.austin.org.au/austinjspui/handle/1/22833
DOI: 10.1016/j.jdermsci.2020.02.003
ORCID: 0000-0002-5111-6367
PubMed URL: 32192826
Type: Journal Article
Subjects: Human leukocyte antigen (HLA)
Pharmacogenomics
Pharmacovigilance
Severe cutaneous adverse reaction (SCAR)
Stevens-Johnson syndrome (SJS)
Toxic epidermal necrolysis (TEN)
Appears in Collections:Journal articles

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