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Three-step two-pot automated production of NCA [18F]FDOPA with FlexLab module. |
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| DOI |
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10.1016/j.apradiso.2019.108871 |
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| Abstract |
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Automated three-step two-pot production of no-carrier-added (NCA) [18F]FDOPA was first implemented in the iPHASE FlexLab module. Decay-corrected radiochemical yield (RCY) of [18F]FDOPA synthesized by this method was 10~14% (n = 7) with a synthesis time of ~110 min [18F]FDOPA was obtained in > 95% of radiochemical purity with a molar activity of ~431 GBq/μmol. With the method successfully implementing on the commercial FlexLab module and its built-in step-by-step activity monitoring, further processes optimization would be achieved. |
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| Citation |
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Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2019; online first: 22 August |
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Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine |
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