Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/22704
Title: Haemodynamic effect of a 20% albumin fluid bolus in post-cardiac surgery patients.
Austin Authors: Cutuli, Salvatore L ;Bitker, Laurent;Osawa, Eduardo A;O'Brien, Zachary ;Canet, Emmanuel;Yanase, Fumitaka ;Ancona, Paolo;Wilson, Anthony;Lucchetta, Luca;Kubicki, Mark ;Cronhjort, Maria;Cioccari, Luca;Peck, Lea;Young, Helen ;Eastwood, Glenn M ;Mårtensson, Johan;Glassford, Neil J;Bellomo, Rinaldo 
Affiliation: Department of Intensive Care, Austin Health, Heidelberg, Victoria, Australia
Issue Date: Mar-2020
Publication information: Critical Care and Resuscitation 2020; 22(1): 15-25
Abstract: To study the cardiovascular effect over 30 minutes following the end of fluid bolus therapy (FBT) with 20% albumin in patients after cardiac surgery. Prospective observational study. Intensive care unit of a tertiary university-affiliated hospital. Twenty post-cardiac surgery mechanically ventilated patients with a clinical decision to administer FBT. FBT with a 100 mL bolus of 20% albumin. Cardiac index (CI) response was defined by a ≥ 15% increase, while mean arterial pressure (MAP) response was defined by a ≥ 10% increase. The most common indication for FBT was hypotension (40%). Median duration of infusion was 7 minutes (interquartile range [IQR], 3-9 min). At the end of FBT, five patients (25%) showed a CI response, which increased to almost half in the following 30 minutes and dissipated in one patient. MAP response occurred in 11 patients (55%) and dissipated in five patients (45%) by a median of 6 minutes (IQR, 6-10 min). CI and MAP responses coexisted in four patients (20%). An intrabolus MAP response occurred in 17 patients (85%) but dissipated in 11 patients (65%) within a median of 7 minutes (IQR, 2-11 min). On regression analysis, faster fluid bolus administration predicted MAP increase at the end of the bolus. In post-cardiac surgery patients, CI response to 20% albumin FBT was not congruous with MAP response over 30 minutes. Although hypotension was the main indication for FBT and a MAP response occurred in most of patients, such response was maximal during the bolus, dissipated in a few minutes, and was dissociated from the CI response.
URI: https://ahro.austin.org.au/austinjspui/handle/1/22704
ORCID: 0000-0003-4993-427X
0000-0001-8739-7896
0000-0002-1650-8939
Journal: Critical Care and Resuscitation
PubMed URL: 32102639
ISSN: 1441-2772
Type: Journal Article
Appears in Collections:Journal articles

Show full item record

Page view(s)

78
checked on Nov 1, 2024

Google ScholarTM

Check


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.