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Title: Anti-NMDAR Encephalitis: Higher Suspicious Needed for Earlier Diagnosis (Case Report, Literature Review and Diagnostic Criteria).
Austin Authors: Amugoda, Chanaka;Chini Foroush, Noushin;Akhlaghi, Hamed
Affiliation: Emergency Physician, St. Vincent's Hospital, University of Melbourne, Melbourne, Australia
Austin Health, Heidelberg, Victoria, Australia
Emergency Department, Werribee Mercy Hospital, Melbourne, Australia
Issue Date: 28-Dec-2019 2019-12-28
Publication information: Case reports in neurological medicine 2019; 2019: 7476254
Abstract: Auto-immune mediated anti-NMDA receptor encephalitis is a very common delayed diagnosed encephalitis which predominately affecting young population. This encephalitis is relatively unknown amongst emergency physicians and a majority of patients are admitted to psychiatric wards before their diagnosis is confirmed and appropriate treatments are commenced. We reported a case of a 22-year-old female presented to our emergency department with acute psychiatric symptoms. She was initially diagnosed with first presentation of acute psychosis and was hospitalised under mental health act. further assessment in the emergency department identified possible an organic cause for her acute psychosis and she was later admitted under medical team after her mental health assessment order was revoke. Several days later, her CSF result was positive with anti-NMDA receptor anti-bodies. Appropriate treatments were instituted leading to her full recovery. This case was the first confirmed anti-NMDA receptor encephalitis in our emergency department. It highlights the importance of thorough assessment of psychiatric presentations to emergency departments and consideration of auto-immune medicated encephalitis as one of the differential diagnosis in young patients presenting with first acute psychotic episode.
DOI: 10.1155/2019/7476254
ORCID: 0000-0002-3929-7265
PubMed URL: 31956454
ISSN: 2090-6668
Type: Journal Article
Appears in Collections:Journal articles

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