Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/22335
Title: Hourly Fluid Balance in Patients Receiving Continuous Renal Replacement Therapy.
Austin Authors: Naorungroj, Thummaporn ;Serpa Neto, Ary ;Zwakman-Hessels, Lara;Yanase, Fumitaka ;Eastwood, Glenn M ;Bellomo, Rinaldo 
Affiliation: Australian and New Zealand Intensive Care Research Center, Monash University School of Public Health and Preventive Medicine, Melbourne, Victoria, Australia
Department of Critical Care Medicine, Hospital Israelita Albert Einstein, São Paulo, Brazil
Department of Intensive Care Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Department of Intensive Care Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
Intensive Care
Department of Critical Care Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
Centre for Integrated Critical Care, The University of Melbourne, Melbourne, Victoria, Australia
Data Analytics Research and Evaluation (DARE) Centre, Austin Health and The University of Melbourne, Heidelberg, Victoria, Australia
Issue Date: 2020
metadata.dc.date: 2019-12-17
Publication information: Blood purification 2020; 49(1-2): 93-101
Abstract: Little is known about early (first 48 h) hourly and cumulative fluid balance (FB) during continuous renal replacement therapy (CRRT). To study the characteristics and outcome associations of early hourly and cumulative FB. We studied FB in CRRT patients (2016-2018). Among 350 patients, mean hourly FB became negative after 20 CRRT hours, but within 6 CRRT hours in patients with baseline fluid overload. A negative early FB was never achieved in patients receiving vasopressor therapy (p < 0.001). Mortality was 31%. The percentage of hourly negative FB was independently associated with decreased ICU mortality. A time-weighted hourly FB between 18.5 and -33 mL/h was also significantly and independently associated with decreased mortality. In CRRT patients, an early FB conservative approach is possible, modulated by patient characteristics, and associated with a low mortality. Moreover, avoidance of an early positive FB is associated with decreased mortality.
URI: http://ahro.austin.org.au/austinjspui/handle/1/22335
DOI: 10.1159/000503771
ORCID: 0000-0002-1650-8939
PubMed URL: 31846982
Type: Journal Article
Subjects: Continuous renal replacement therapy
Fluid overload
Hourly fluid balance
Mortality
Vasopressors
Appears in Collections:Journal articles

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