Austin Health

Title
Treatment selection for first-line metastatic renal cell carcinoma in Australia: Impact of new therapy options.
Publication Date
2019-11
Author(s)
Schmidt, Andrew
Azad, Arun
Goh, Jeffrey
Harris, Carole
Joshua, Anthony M
Weickhardt, Andrew
Krieger, Laurence
Subject
VEGF tyrosine kinase inhibitors
immuno-oncology
renal cell carcinoma
Type of document
Journal Article
DOI
10.1111/ajco.13289
Abstract
Vascular endothelial growth factor receptor tyrosine kinase inhibitors have provided an effective standard of care for the treatment of metastatic clear cell renal cell carcinoma (mRCC). Survival is prolonged with emergence of modern immuno-oncology combination regimens. Prognostic risk assessment is essential for choosing between these therapies to determine the most appropriate first line treatment option, with selection based on International Metastatic RCC Database Consortium Risk Category. We review the current subsidized first line treatments for mRCC in Australia and consider the evidence for treatment selection and sequencing.
Link
Citation
Asia-Pacific journal of clinical oncology 2019; 15 Suppl 10: 3-10
Jornal Title
Asia-Pacific journal of clinical oncology

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