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Title: Novel Target Selection for Nuclear Medicine Studies.
Austin Authors: Lee, Sze Ting ;Burvenich, Ingrid J G;Scott, Andrew M 
Affiliation: School of Cancer Medicine, La Trobe University, Melbourne, Australia
Faculty of Medicine, The University of Melbourne, Melbourne, Australia
Department of Molecular Imaging and Therapy, Austin Health, Heidelberg, Victoria, Australia
Olivia Newton-John Cancer Research Institute, Austin Health, Heidelberg, Victoria, Australia
Issue Date: Sep-2019 2019-07-06
Publication information: Seminars in nuclear medicine 2019; 49(5): 357-368
Abstract: Nuclear medicine techniques involving SPECT and PET are being increasingly used as a noninvasive tool for the detection, quantitation and therapy response monitoring of a myriad of disease processes through target visualization and kinetic modeling. The target selection requires a good understanding of the physiologic changes involved in the disease processes. The target selected can range from cellular proteins expressed in a particular organ, biochemical pathways in cells, or receptors on circulating blood cells. This can have a significant impact on therapeutic options for subsequent therapies, including radionuclide therapies in this evolving world of theranostic practices, which is outlined in this review.
DOI: 10.1053/j.semnuclmed.2019.06.004
ORCID: 0000-0001-8641-456X
PubMed URL: 31470931
Type: Journal Article
Appears in Collections:Journal articles

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