Austin Health

Title
New Advances in the Management of Cytomegalovirus in Allogeneic Haemopoietic Stem Cell Transplantation.
Publication Date
2019-08-12
Author(s)
Yong, Michelle K
Gottlieb, David
Lindsay, Julian
Kok, Jen
Rawlinson, William
Slavin, Monica
Ritchie, David
Bajel, Ashish
Grigg, Andrew P
Subject
CMV immune monitoring
CMV-specific T cell therapy
Cytomegalovirus
haemopoietic stem cell transplantation
letermovir
maribavir
Type of document
Journal Article
OrcId
0000-0002-8692-4145
0000-0002-4674-3403
DOI
10.1111/imj.14462
Abstract
Cytomegalovirus (CMV) viremia continues to be a frequent complication in the post haemopoietic stem cell transplant (HSCT) period despite a low incidence of CMV end-organ disease. A number of significant advances in the understanding and management of CMV infection have occurred in the last few years including improved diagnostics, monitoring of CMV immunity, availability of novel anti-CMV drugs, and emerging use of immunotherapies including CMV-specific T cell infusions. In addition to reviewing these advances we also explore some of the more practical prescribing issues of the older and newer CMV drugs including cost, toxicity and drug interactions to help clinicians navigate this new era of CMV management. This article is protected by copyright. All rights reserved.
Link
Citation
Internal Medicine Journal 2020; 50(3): 277-284
Jornal Title
Internal Medicine Journal

Files:

NameSizeformatDescriptionLink