Austin Health

Title
Screening and Prophylaxis to Prevent Hepatitis B Reactivation: Introduction and Immunology.
Publication Date
2019-08
Author(s)
Sasadeusz, Joe
Grigg, Andrew P
Hughes, Peter D
Lee Lim, Seng
Lucas, Michaela
McColl, Geoff
McLachlan, Sue Anne
Peters, Marion G
Shackel, Nicholas
Slavin, Monica
Sundararajan, Vijaya
Thompson, Alexander
Doyle, Joseph
Rickard, James
De Cruz, Peter
Gish, Robert G
Visvanathan, Kumar
Subject
Adaptive
Hepatitis B immunology
Hepatitis B virus
Innate
Prophylaxis
Reactivation
Type of document
Journal Article
DOI
10.1016/j.cld.2019.04.009
Abstract
Current recommendations concerning hepatitis C virus (HBV) reactivation are limited, with nearly all guidelines focused on its occurrence in patients with hematological malignancies or some solid tumors, who are treated with immunosuppressive therapies. Few of the guidelines address reactivation in patients receiving immunosuppression with organ transplants or treatment with any of the many immunosuppressive agents in use today for the treatment of multiple different diseases, or in patients receiving the direct-acting antivirals used in the treatment of hepatitis C virus (HCV). This article covers the immunology of HBV reactivation, mechanisms of viral clearance, and recommendations for screening and prophylaxis.
Link
Citation
Clinics in liver disease 2019; 23(3): 487-492
Jornal Title
Clinics in liver disease

Files:

NameSizeformatDescriptionLink